Protein Alignment tacc and tacc1

DIOPT Version :9

• Sequence 1: NP_001189169.1
• Gene: tacc / 40589
• FlyBaseID: FBgn0026620
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: XP_021334997.1
• Gene: tacc1 / 565711
• ZFINID: ZDB-GENE-090521-5
• Length: 769
• Species: Danio rerio
• Alignment Length: 1043
• Identity: 225/1043 - (21%)
• Similarity: 373/1043 - (35%)
• Gaps: 354/1043 - (33%)

  Fly   335 AKESESLVESVLSEESGT---QSFEPKLTLSALDSTKDLAKHQEEMQTNTKDIFQKEKHHPVSSA 396
            ||.:.|.|.....||..|   ...|| ||..|.::   :.::||:          .|:.|..||
Zfish    10 AKWTWSAVRGGGEEEGETDLGMDDEP-LTEEARET---IPRYQED----------DERSHGCSS- 59

  Fly   397 QVKDAQNPKE-PEKALNLKEASSELSTKSAKSLEYPNQEKQ-FSVAVESMERPCTAISLEQNASP 459
               |::...| ||....:.:...|||     :|:.|..|.. ||   |......|||:.:
Zfish    60 ---DSEGQFETPEAETPVHQPFKELS-----ALDQPITESSGFS---EEYVNHLTAITTK----- 108

  Fly   460 AMEATEDRTVEELDQMDVDESMKVDDATVLNSCRQEQINAHSPVSSKFFLKLCVQNDTDCQDNKM 524
                |::.|:|:....|.       .||||   ||..:::...:..|:.|. .|..|.|..|  .
Zfish   109 ----TQNLTLEKSFAEDA-------PATVL---RQSSLDSTPTLKPKYQLS-SVDMDVDQPD--P 156

  Fly   525 DQKTAGKESALKMTEIELPVESVPSASLSPPTPALQAKI-------IELSLSPPIPTHRPKTAEE 582
            |...|.:.|.:....||.|.....:.||....|:||.|.       .|:...|||   .||.:..
Zfish   157 DDAGATEHSNICNGHIEEPSSKPQTKSLKVRPPSLQVKSPLNGVDPNEVDDDPPI---LPKGSYN 218

  Fly   583 LEFLALREL--PLPDGVSTAGKVECKQLSHGLVP---IVAVLPT-PLYLDL-------------- 627
            .:...:.|.  |.|.|.|   |::....::..:|   ::..:|. |:.|:.
Zfish   219 FDLDQVNETMNPFPTGGS---KLQNSPPANASIPKSELMDEMPAQPVLLEFGLDDTEVKTDPPKK 280

  Fly   628 KGNTTTASL-------PEPTSPSFPIKEPAEKQSHFPRSPRAQLEQKDMPYLEEAVVERSSHRKQ 685
            .|..|::.|       |:....:.|:.|.:.:||..|.      |..|:..:::..:.:.|:.
Zfish   281 SGKKTSSKLTTPKKLRPKAAETAAPLPETSSEQSQQPP------ENADLINVDDIPIPKKSYN-- 337

  Fly   686 SDFGVIAKSPIVFELTQ-------PSPEKQHLNE--TLPMSEIS--PTSSNMTFDSGSITEDKSQ 739
                        |:..|       |...||.|:.  |||....|  |.    |||. |:...||.
Zfish   338 ------------FDPNQWDDPNFDPFGGKQKLSSSPTLPKGSYSFDPD----TFDD-SVDPFKSS 385

  Fly   740 KGTENIEPSSTLAVSLGSVDDKQRRTFSVVQPTKEEEEAKSRRTFCMENENPRRTFCMQQNASPA 804
            |             |||..|.        |:||.|:...|                 ::.:.:|
Zfish   386 K-------------SLGGSDS--------VKPTSEKLTEK-----------------LKSDGTP- 411

  Fly   805 VEATEDTGADEVMDVDISMRADEVAVMKSHQQTWKERQAPISNSPPIPTHQRLNRPPEAISPVSP 869
                                          :|..|..|:|..:.      .|:....|.:..:..
Zfish   412 ------------------------------EQRKKAGQSPKKSK------DRILTTTEQVRFLCF 440

  Fly   870 LGNGTVV--LEEQTLSAKEQATLSASDEKDDVFLEHFGAISPVSDDMFKTSSASNNQAKFRVNAD 932
            |.|...|  .|.|:|      .|...|:::||                :..|.|....:.....|
Zfish   441 LLNSCKVKKYENQSL------VLDVCDQENDV----------------QEDSGSKLSNRVHHATD 483

  Fly   933 EETGGKGASAMIRKRSGTAGEQEEIFDAEFHDGVNNQNLILNSSDFDYLY-----TKGSNSVPID 992
            ||   |.||.::.::.||         .||.|                 |     ||.::.:|:.
Zfish   484 EE---KLASTVMIQKDGT---------EEFSD-----------------YKTTTCTKTADDLPVG 519

  Fly   993 RSSLLLKFDPLLGAPVPVNHPNQQEQALQNILGSNQHQNRLLSPTLEEHETSDGNQSFGVISSAK 1057
                                                     ::...||.:.|..::|.
Zfish   520 -----------------------------------------ITEQFEEKDLSSPSESL------- 536

  Fly  1058 DTAKKWDFKPPVDRTKKHVKMSVDVIDNDCNK-TFDNSNTNTEDKTHNYND---MDELEKKIKNE 1118
                                         |.. |..:|::.|..||....|   :.|::|.....
Zfish   537 -----------------------------CKSYTLSSSDSETIVKTSPGLDSIPLSEIDKAAVLT 572

  Fly  1119 VTRSEDIEKKLKEGELR---EEALIKRITEKDKTNAKLNGVIEAYEKAIAELISEKEQQAQLHER 1180
            :.|.|.|.|:::..|.:   ||..:: :||..|       :::.|||.:|::|.:::::....::
Zfish   573 LIREEIIAKEIEANEWKRKYEEGKLE-VTEMRK-------IVDEYEKTVAQMIEDEQRKNIGSQK 629

  Fly  1181 QLQEVQADRDANYHHLTSLETTFSDLHVKYEKSKEMTSQLKSNEESLLAERKQMMDNLRLQEQRY 1245
            .:|::..:||.....|.|:|.:.|||..:||..|.:....|.|||.|....:..:..:|.:||||
Zfish   630 SVQQLTLERDQALADLNSVERSLSDLFRRYENMKTVLEGFKKNEEVLKKCAQDYLTRVRQEEQRY 694

  Fly  1246 DKMKNHAMQQLEIANKKLDTYSREHADETKKLKALLKKEEISRVSMTEQLQQKSRENADLLKICE 1310
            ..:|.||.::|:.||:::.....:...|:..|.|.|:||::...|:...|:||::|..:|.|||:
Zfish   695 QTLKIHAEEKLDKANEEIAQVRSKANAESVALNASLRKEQMKVDSLERALEQKNQEIEELTKICD 759

  Fly  1311 ELI 1313
            |||
Zfish   760 ELI 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tacc	NP_001189169.1	TACC	1103..1313	CDD:282818	62/215 (29%)
tacc1	XP_021334997.1	TACC	563..762	CDD:309929	61/206 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6722
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002147
OrthoInspector	1	1.000	-	-		otm25358
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13924
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9199
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	8.000