Protein Alignment tacc and Tacc3

DIOPT Version :9

• Sequence 1: NP_001189169.1
• Gene: tacc / 40589
• FlyBaseID: FBgn0026620
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: XP_006251391.2
• Gene: Tacc3 / 360962
• RGDID: 1302948
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 876
• Identity: 182/876 - (20%)
• Similarity: 326/876 - (37%)
• Gaps: 256/876 - (29%)

  Fly   509 LKLCVQNDTDCQDNKMDQ---------KTAGKESALKMTEIELPVESVPSASLSPPTPALQAKII 564
            :.|.:..|.:..:.|..:         :..|:.|.|::::    .|:||        |..|||..
  Rat     1 MNLHILTDENVPNEKSSESRDFLFSAPELTGRSSVLRLSQ----KENVP--------PKNQAKAA 53

  Fly   565 ELSLSPPI---PTHR---PKTAEELEFLALRELPLPDGVSTAGKVECKQLSHGLVPIVAVLPTPL 623
            :::...|:   .|||   |....:||    ....|.|.|..       |..|.:.
  Rat    54 KVTFQTPLRDPQTHRILSPNMTSKLE----APFALDDSVGL-------QNDHCVF---------- 97

  Fly   624 YLDLKGNTTTASLPEPTSPSFPIKEPAEKQSHFPRSPRAQLEQKDMPYLEEAVVERSSHRKQSDF 688
               |:...|..|.|         :..||:....|...:::..|:..|...|   ||...|:::
  Rat    98 ---LQKENTKVSSP---------RRLAERPGLQPLLKKSETSQEQCPKETE---ERDGTRERN-- 145

  Fly   689 GVIAKSPIVFELTQPSP-EKQHLN-ETLPMSEISPTSSNMTFDSGSITEDKSQK----------- 740
                      |..||:| ...||| |.|.....:|..|:..::.......:|.|
  Rat   146 ----------ECPQPTPWGSYHLNWEKLDDPNFNPFGSDSKYNGQKAKLPESPKNRLSLPVAEQL 200

  Fly   741 --GTENIEPSSTLAVSLGSVDDKQRRTFSVVQPT----KEEEEAKSRRTFCMENENPR--RTFCM 797
              |..::|.|.:..:.:..|||     ..|||..    |.|:|.:..   .:.:.:|.  .:|..
  Rat   201 SAGPTDVESSPSHQLPVAPVDD-----VPVVQMAAEILKAEDELQEG---ILNSLSPSAFTSFPD 257

  Fly   798 QQNASPAVEATED---TGADEVMDVDISMRADEVAVMKSHQQTWKERQAPISNSPPI-PTHQRLN 858
            .:..:|.:|...:   .|.:.::|.:                       |:  :||: |..:...
  Rat   258 GELVTPPIEPMPEPSPQGPEPLLDSE-----------------------PV--TPPVKPVLEPTP 297

  Fly   859 RPPEAI-------SPVSPLGNGTVVLEEQTLSAKEQATLSASDEKDDVFLEHFGAISPVSDDMFK 916
            :.||.:       .||.|:...|....|..|.: |..||......:.   .|.|. .|:.|
  Rat   298 QGPEPLLDSEPVTPPVKPVLEPTPQGSEPLLDS-EPVTLPVEPVPES---SHQGP-EPLLD---- 353

  Fly   917 TSSASNNQAKFRVNADEETGGKGASAMIRKRSGTAGEQEEIFDAEFHDGVNNQNLILNSSDFDYL 981
                 :......|....|:..:|...::..:..:..:..|:..|              .::.|||
  Rat   354 -----SEPVTLPVEPVPESSHQGPEPLLDPKEESFRDPAEVLGA--------------GAEVDYL 399

  Fly   982 YTKGSNSVPID---RSSLLLKFDPLL------GAPVPVNHPNQQEQALQNILGSNQHQNRLLSPT 1037
            ...|::|....   :.||.|||||||      ..||||                    ..:.:.|
  Rat   400 EQFGTSSFKESAWRKQSLYLKFDPLLKESPLRSMPVPV--------------------APVTNST 444

  Fly  1038 LEEHETSDGNQSFGVISSAKDTAKKWDF-----------KPPV----DRTKKHVKMSVDVIDNDC 1087
            .:..|:..||.:         .||..|.           .||:    .|.....:..|||:
  Rat   445 QDTEESGSGNPT---------EAKLVDLDFLGGLDVPVSAPPLCVLEPRGLLPAEPIVDVL---- 496

  Fly  1088 NKTFDNSNTNTEDKTHNYNDMDELEKKIKNEVTRSEDIEKKLKEGELREEALIKRITEKDKTNAK 1152
                          .::..|:|.:.     .|.:.|::|.:.|..:|..:.|            :
  Rat   497 --------------KYSQKDLDAVV-----NVMQQENLELRNKYEDLNTKYL------------E 530

  Fly  1153 LNGVIEAYEKAIAELISEKEQQAQLHERQLQEVQADRDANYHHLTSLETTFSDLHVKYEKSKEMT 1217
            :..:::.:||.:.:.:.|.|:|.:|.|.::|::..:||.....|.|:|.:||||..::||.||:.
  Rat   531 MGKIVDGFEKIVYKSMEEAEKQKELAEDKIQKILRERDQLTADLNSMEKSFSDLFKRFEKQKEVI 595

  Fly  1218 SQLKSNEESLLAERKQMMDNLRLQEQRYDKMKNHAMQQLEIANKKLDTYSREHADETKKLKALLK 1282
            ...:.||:||....:..:..:..:.|||..:|.||.::|::||:::.....:...|...|:|.|:
  Rat   596 EGYQKNEDSLKKCVEDYIVKIGKEGQRYQALKAHAEEKLKMANEEIAQVRSKAQAEALALQASLR 660

  Fly  1283 KEEISRVSMTEQLQQKSRENADLLKICEELI 1313
            |.::...|:.:.::||::||.:|.:||:|||
  Rat   661 KAQLQIQSLEKTVEQKTKENDELNRICDELI 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tacc	NP_001189169.1	TACC	1103..1313	CDD:282818	56/209 (27%)
Tacc3	XP_006251391.2	PHA03247	<248..492	CDD:223021	58/325 (18%)
		TACC	498..691	CDD:398605	56/209 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002147
OrthoInspector	1	1.000	-	-		otm46183
orthoMCL	1	0.900	-	-		OOG6_106926
Panther	1	1.100	-	-	LDO	PTHR13924
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.910