Protein Alignment Nep2 and Nepl19

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 171/735 - (23%)
• Similarity: 301/735 - (40%)
• Gaps: 155/735 - (21%)

  Fly    80 SGDVCLTQECIH-TASTVLRK-MKPEVEPCDNFYEFACG----------TYLEEENIPDDKVSIS 132
            |.|....|..:. :.|..:|. |:.:.:.|:|||:::||          .|..|.|..  ::.:.
  Fly    47 SNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFV--QLLLK 109

  Fly   133 TFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKAC-MNKTLIETLGPEPITRVAERLGGWP 196
            .:|....:|.||..::.|.|......|.|      |.:| :.:.:.|.|....:..:....|..|
  Fly   110 AYSHKQQRLMEQPANVETDEVAVLRLKEF------YASCLLFRQVPEDLYRRQLQEIVADFGRMP 168

  Fly   197 LIK--GDSWNADDSWTWQEQVKKF-RTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREY 258
            ::.  |..|.|:: :.|.:.|.:. |..||  |.::.|      |.|..| |.:.|....|. |.
  Fly   169 VLSLPGQEWPAEE-FDWLDTVARIKRQYGF--DILLLF------QQSADR-IYVGQPKQILP-EA 222

  Fly   259 LVKGFNETLVTAYYKYM-VDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNL 322
            ..|...|.:.....::: ||..|.....|::.        |||..:|.|.    ..|....:..|
  Fly   223 NRKAVAEDIANHLERHLGVDPKVAVTTAREIT--------EFEQKIAAIM----VDRRVGVMSKL 275

  Fly   323 RTPAQLQAAYPYV-QWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFW 386
            .||:  .|.|..| :...::..:|...|  ..:|.:...||.:...:.:|:.:||..|:|||:|
  Fly   276 YTPS--DADYVDVSKLTQFVETVLDREL--LANESLYQHVPDYLMKIDELVTETPPHVLANYVF- 335

  Fly   387 RIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECV----DIATSSMDEVCEDDFDSLGISV 447
                       .|..| ...|..|       |:..::||    |:....:|.:..:.::..| ::
  Fly   336 -----------NELLK-HFYYERA-------ESVVEQCVSRVRDLFGELLDHMLFEQYEDEG-TL 380

  Fly   448 GSLYVGKHFHKDSKANALEMVNEIRNVFNDIL--DEVNWMDAKTKKEAKLKLHSMATHI-GYPDE 509
            ..:||              :..:::..|..:|  ...||:..:|:::...:|::.:..| ||.:
  Fly   381 KDIYV--------------VWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAE- 430

  Fly   510 MLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSL 574
                ......|.:|.:.|..|..:      ..|..:...||:.| ||.         .:..|..:
  Fly   431 ----VNFTQRYEELHLKPRDYLHN------LRTILNHQSLRVKV-KTQ---------TSVTYDPV 475

  Fly   575 ENSIQFPAGILQGHF-FNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQK 638
            ...:..|..:||.:| ::...||.:.:|::|.::..::.|..:|..:           |...:..
  Fly   476 GKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFA 529

  Fly   639 AYLAKAKCIIEQYGNYTERATGLNLNG-----INTQGENIADNGGVKESYIAYRRWAEKHGP--- 695
            .|..:..|..||||.       |.|||     .:.|.||||||..::.:|.||||...:..|
  Fly   530 EYSKRKSCFKEQYGR-------LRLNGHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFL 587

  Fly   696 -EAKLPGLDYTPEQMFWVAAGQTWC----AKYR-KESLKMRITTGVHSPSEFRVLGSLSNMKDFA 754
             ...||.|:....::|:::..|.||    .::| |:||.:      .:|:..||||:|||.:.|.
  Fly   588 GSESLPQLNLGSRRLFFLSFAQLWCNDANEQFRDKQSLFL------GTPNALRVLGALSNFRAFG 646

  Fly   755 KDFHCPEGSPMNPVQKCEVW 774
            :||:|...|.|...|||:::
  Fly   647 RDFNCGTASRMTSPQKCQLF 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	164/705 (23%)
Nepl19	NP_651644.1	M13	73..664	CDD:341056	164/705 (23%)