Protein Alignment Nep2 and Nepl17

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 787
• Identity: 181/787 - (22%)
• Similarity: 318/787 - (40%)
• Gaps: 148/787 - (18%)

  Fly    21 LLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGDSTTINQVPTGTASKGKSGDSGDVCL 85
            |..|..::||.||.|                  :.|:.|........|.|.... :...|.::|
  Fly     4 LPASACLIFVTLAVG------------------SLAIQGGVFKELTTPLGQQIM-RIAKSAEMC- 48

  Fly    86 TQECIHTASTVLRKMKPEVEPCDNFYEFACGTYL---EEENIPDDKVSISTFSVISDKLQEQLKD 147
                        ..|...|.|||:||.:|||.|.   ...:..|..:....|:....::::.|.:
  Fly    49 ------------SFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQLMFANYLRRVRQVLNE 101

  Fly   148 -IITAERP-ETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWN---ADD 207
             .|:.:|| |...|:|      |::|::...:.|.....:..|....||.|.::|.||:   .|.
  Fly   102 PRISTDRPMEVRVKYF------YESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDA 160

  Fly   208 SWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQS-SLALSREYLVKGFNETLVTAY 271
            .....:.::::........|::.     |..||..:.:.|.|. .||.|.|:         .:.:
  Fly   161 IEMMAQLLRRYGKLTLLGVYVVP-----DHFNSQIKRLQLGQRLDLAESDEF---------ASLW 211

  Fly   272 YKYMVDIAV--LFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAY-P 333
            .||.:.:.:  |.|.:.:||:......:|.|:.|:..::.:...|:...:.:|...:.:..|| |
  Fly   212 KKYALKMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGP 276

  Fly   334 YVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSE 398
            .:....::.:.|....|:...|    ||||:...:.|:|..||..|:||||        :..|..
  Fly   277 ILNVTRFVTSWLGSEYNLPVFE----SVPSYLFQVKKILLSTPNHVVANYM--------LSSLLT 329

  Fly   399 EFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKAN 463
            :|.         ::..:||:              ..:|.:....|...|....|.....:.:...
  Fly   330 DFE---------ITANEEQQ--------------KVICHERITELFPDVVDHMVYHSLEQQNPYI 371

  Fly   464 ALEMVN---EIRNVFNDILD--EVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKL 523
            |.||.:   |:::.|.::|.  ::.|::.:|::|...||:.|:..|.....:
  Fly   372 ANEMRSLWVELKSSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAV------------- 423

  Fly   524 DIDPDKYFESFLGMNIFGTDYSFNKLRL-----PVNKTDWVRHA------RPAIVNAFYSSLENS 577
                 .:.|.|..:.:...||..|..||     .:.:||.:|.:      ........|.:..|.
  Fly   424 -----NFEEQFGDLVVSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTATPIYETETNL 483

  Fly   578 IQFPAGILQGHF-FNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYL 641
            :..|...:|..: ::...|..:.:|.:|:.:.||:.|||||..|.:|.:|||.|.|...|:..:.
  Fly   484 VVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFE 548

  Fly   642 AKAKCIIEQ-----YGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPE--AKL 699
            ....|:.:|     |||       |.|..:.:|.|:||||.|::.:..||.:|.::...|  ..|
  Fly   549 LVKNCLADQFSGMLYGN-------LRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESL 606

  Fly   700 PGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSP 764
            |.:..:|||:|:::|.|..|:....|.....:....|.|.|.||...:.|...||:.|.|...|.
  Fly   607 PHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSK 671

  Fly   765 MNPVQKC 771
            |||..||
  Fly   672 MNPPNKC 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	167/704 (24%)
Nepl17	NP_651641.1	M13	55..678	CDD:341056	165/702 (24%)