Protein Alignment Nep2 and Nep5

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 784
• Identity: 210/784 - (26%)
• Similarity: 358/784 - (45%)
• Gaps: 116/784 - (14%)

  Fly    80 SGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQ 144
            |..:|.::||:.||::::..|..:.:||::||:|.||.:..|...||...|...|......:...
  Fly   126 SSSICRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRV 190

  Fly   145 LKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLI---------KG 200
            :::.:.:...::||:.......:|:|||:..|::....||:.....|. |.|::         .|
  Fly   191 VREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRF-GLPVLPSALNLTLGSG 254

  Fly   201 DSW---NADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDL-------------DQ 249
            ..:   .|:..:.|.:.:...: ...:||.||.|.:..|..|.|...|.|             |.
  Fly   255 SKYATEAANVKYNWLQSIVSIK-QHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNNDD 318

  Fly   250 SSLAL------------------------SREYLVKGFNETLVTAYYKY---MVDIAVLF---GA 284
            |...|                        |.|........|.:|||..|   :::..:|:   ..
  Fly   319 SHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVDPNV 383

  Fly   285 NRD---LAKTELLLS--------LEFEMALANISWPNEKRRNSSE------LYNLRTPAQLQAAY 332
            |::   |..|||:..        .||:....|::.|:   :|.::      |.:|:.......|.
  Fly   384 NQEEATLGITELVKQGVRVARKVHEFKEEAENMTKPS---KNPADDIVYITLQDLQNQTDKNIAP 445

  Fly   333 PYVQ-WVDYMNALLPEGLNVAEDEMI-NLSV------PSFFEDLGKLLAKTPKRVIANYMFWRIH 389
            ..:. ||.||..:|....:....:|. ||::      .::.:::.:.|..||...|.:|:|....
  Fly   446 KTLPIWVRYMELILKGTRHAGNIQMTQNLTIITSQADITYLQNIVEYLDDTPASHIESYLFLSTI 510

  Fly   390 GFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGK 454
            ...|...|...|....:|.....|.:....|...|.:...|           .||::|..:....
  Fly   511 EELVLHTSSSMRLLHSEYMRVAIGTEGSTPRSLYCANGVNS-----------LLGMAVSYVLADA 564

  Fly   455 HFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAY 519
            .|.|:.......|:::||..|:.::...:||||.||::...|...|.:.||:|..:.:...|.||
  Fly   565 DFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKRKTIQKSAEMKSFIGFPPWLRNASVLNAY 629

  Fly   520 YAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTD------WVRHARPAIVNAFYSSLENSI 578
            |...:::...:.|:.:       |:...::...:|:.|      |.  ..|:.||||::...|:|
  Fly   630 YEGAEVNASTHLENLM-------DFVHWQMMDKLNEMDKPEPIGWA--TSPSNVNAFHTFQSNAI 685

  Fly   579 QFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAK 643
            ..|..|||..|::... :.:|:|:||.::|||:||||||.||:||..||:.:||...|...|:.:
  Fly   686 TVPIAILQYPFYDLGL-EALNYGSIGTILGHELTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNR 749

  Fly   644 AKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPE-AKLPGLD-YTP 706
            .:|.:|||..|........::|..|.|||||||||::|::.|||.:.::.|.| :|||||: |:.
  Fly   750 TECFVEQYSRYHLADIDEYIDGELTLGENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSH 814

  Fly   707 EQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQ-K 770
            ||:|:::.|..||..|...:.:..:|.. |.|.:.|:.|.|||.::||:.|.|..|:||||.| |
  Fly   815 EQLFFISFGNLWCETYTPAASRYALTDS-HCPGQMRLRGVLSNSEEFARTFKCARGTPMNPDQPK 878

  Fly   771 CEVW 774
            |.:|
  Fly   879 CRIW 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	201/756 (27%)
Nep5	NP_733186.2	M13	151..880	CDD:341056	201/755 (27%)