Protein Alignment Nep2 and Nepl13

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 170/820 - (20%)
• Similarity: 303/820 - (36%)
• Gaps: 239/820 - (29%)

  Fly    75 GKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFAC---GTYLEEENIPDDKVSISTF-S 135
            |...||.:..|.::.|  |:.|.:.|....:||.:|:|:||   |.|.:.:..||:   :||. .
  Fly    41 GNFPDSREEQLVRQKI--ATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDE---LSTAQQ 100

  Fly   136 VISDKLQEQLKDIITAERPETEPKHFRLPN--------------LLYKACMNKTLIETLGPEP-- 184
            ::..|:.|||:.::|...|   |:|.  ||              ..|::|:   .:|....|.
  Fly   101 LMETKISEQLQQLLTQPLP---PQHH--PNGYSGASMTNVRKVRAFYESCV---AVEANASERRR 157

  Fly   185 -ITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAG-----FSMDYIIDFSIGVDLQNSTKR 243
             :.::.:..||...:...:|..:..|.        :|.|     :.:|.::...|.::||.....
  Fly   158 FLMKILKDNGGLRNVPNSNWQHNRQWV--------QTLGELRRNYGLDILLGLEIDLNLQTMKGN 214

  Fly   244 LIDLDQSSLAL----------SREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTEL--LLS 296
            .|...:..|.:          :|...|:  :|.......:...::...||.:...|....  ::.
  Fly   215 TIYFGEPKLTIIPAEHCNALATRGAQVR--DEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIR 277

  Fly   297 LEFE----MALANISWPNEK---------------------RRN---------SSEL-----YNL 322
            .|||    |...:|..|.|:                     ||.         :||:     :.:
  Fly   278 FEFELCKQMGEQDIQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKM 342

  Fly   323 RTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWR 387
            .....|::.||                     ..:.|..|.:.:.:.:.:....:..:..|:.:
  Fly   343 LVEVILESQYP---------------------SQVYLRSPEYVKHVVRTVKANNRITVGGYILY- 385

  Fly   388 IHGFSVGFLSEEFRKRQLQYATALS--GRQEQEA---RWKECVDIATSSMDEVCEDDFDSLGISV 447
                                 .||:  .:..:||   |.::||.:......:|..:.|.
  Fly   386 ---------------------VALNELNQPPEEAPSQRARQCVQVTQRLFPQVLGEMFQ------ 423

  Fly   448 GSLYVGKHFHKDSKANALEMVNEIRNVFNDI---LDE---VNWMDAKTKKEAKLKLHSMATHIGY 506
                  :|..:|:..:.|:.      ||||:   |:|   |.|||...::.|:.:|...  .:..
  Fly   424 ------RHVQRDNAKHDLDA------VFNDVIKALEEQFHVEWMDENDRRAARTRLSQY--RVSL 474

  Fly   507 PDEM------LDNEKLAAYYAKLDIDPDKY-----FESFLGMNIFGTDY----SFNKLRLPVNKT 556
            ||..      |..:|...|:.:|:| ..||     ||:..| |.||.|.    :|.
  Fly   475 PDYQSLDLTDLQFQKSEDYWRRLEI-ALKYRSHQQFEALRG-NDFGQDADGLDAFE--------- 528

  Fly   557 DWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQ 621
                      |.|..|..:..:....|:||..::|...||.:.:..:|:.:...:...|||:|
  Fly   529 ----------VRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG-- 581

  Fly   622 FDVKGNLRDW---------WHPDTQKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNG 677
                     |         |:..|...|...::|...||.:|.....|...|....: |.|||..
  Fly   582 ---------WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATRLR-EIIADGS 636

  Fly   678 GVKESYIAYRRWAEKHGPEAK-------LPGLDYTPEQMFWVAAGQTWC-AKYRKESLKMRITTG 734
            |:..::.||..|.|:...:.:       |..|::|..|:|::...||.| ||..::::...:...
  Fly   637 GLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLM 701

  Fly   735 VHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774
            .|:|..:.|.|.|||..:|.::|.|..|:|||...||.|:
  Fly   702 QHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	160/787 (20%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	159/786 (20%)