Protein Alignment Nep2 and Nepl12

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 185/735 - (25%)
• Similarity: 309/735 - (42%)
• Gaps: 156/735 - (21%)

  Fly   100 MKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISD------KLQEQL---KDIITAERPE 155
            |...||||:||||:|||.|   .|:..|:.|..:.|.:.|      .:.|||   .|:..|....
  Fly    64 MNQSVEPCENFYEYACGNY---RNVKPDRYSPGSRSNLGDVTYTLIDITEQLLGRMDLAEALNVS 125

  Fly   156 TEPKHFRLPNLLYKACMNKTLIETLGPEP-ITRVAERLGGWPLIKGDSWNADD-SW--------- 209
            :|   ..:....|.||:...|......:| ...:...:||:|.:.||:|.|.: :|
  Fly   126 SE---LAVAQRFYNACLGANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKASNFNWINMSAHLAN 187

  Fly   210 ---------TWQ-----EQVKKFRTAGFSMDYIIDFSIGVDLQNSTK--RLIDLDQSSLALSREY 258
                     |.|     |...|....||  |:||.....:. :|:|:  ||
  Fly   188 YGANGLIRETLQLRYPFEPYTKLPELGF--DHIIVHEENIS-RNTTRAFRL-------------- 235

  Fly   259 LVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANI--SWPNEKRRNSSELYN 321
                 ||..:..|.:       .||...|          ....|:|.:  .|     |::.|:
  Fly   236 -----NEERMHGYLR-------AFGLPED----------RIREAIAGVFAFW-----RDALEI-- 271

  Fly   322 LRTPAQLQAAYPY-VQWV----DYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIA 381
               |.|.:...|| ::.|    :|...:...||:...    .|....::.:|.|:.|: .::.:|
  Fly   272 ---PPQCEVFDPYRIKRVFPQSEYYYNISWSGLHSTN----KLFCDFYYVELDKVCAR-HRKAVA 328

  Fly   382 NYMFWR-IHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGI 445
            ||:..: ::.|.....:..:::.......                              :.|:..
  Fly   329 NYLAMKLLYRFDPKLKAPRYQRNYCSVTL------------------------------YQSMRF 363

  Fly   446 SVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIG-YPDE 509
            ....||:..:|.:..:....|||.|:|......|::.:|:||:::..|.||...:...|| :.|:
  Fly   364 LFNKLYMANNFSEAKRLEMSEMVRELRKSLRKALEDADWLDAESRARALLKESRIQPRIGSFQDD 428

  Fly   510 MLDNEKLAAYYAKLDIDPDKYFESFLGM-------NIFGTDYSFNKLRLPVNKTDWVRHARPAIV 567
            .| ::::......|.:..|:|.|:.:.:       |.|.:.: |.:|   .|.|...:......|
  Fly   429 AL-SDRIIREINSLKVIEDRYAETNINLQHLVVQINRFSSRH-FQEL---TNDTKPQKILTGLQV 488

  Fly   568 NAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWW 632
            .|.|.:.:|||...||:::...:....|..:.||.:|:::|||:.||||.....||..|::....
  Fly   489 GAGYYTPDNSINVMAGVVEPPIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLL 553

  Fly   633 HPDTQKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYR----RWAEKH 693
            ...:|:|...:|:|.::.||.|........:||..|..||||||.|::::..|||    :..|..
  Fly   554 SEISQQALEDRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHP 618

  Fly   694 GPEA---KLPGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAK 755
            |.|.   .:||||.||||:|::...|.:|:.|.:|.. .:..:.||:..:|||||.|||.:||..
  Fly   619 GQERISDAMPGLDLTPEQLFFLGFAQLFCSHYEEEHY-WKGLSDVHTFDQFRVLGVLSNSEDFFH 682

  Fly   756 DFHCPEGSPMNPVQK-CEVW 774
            .::|..||.|.|..| |.:|
  Fly   683 AYNCSVGSGMRPGAKTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	182/727 (25%)
Nepl12	NP_649924.1	M13	68..700	CDD:189000	182/727 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920