Protein Alignment Nep2 and Nepl11

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 138/704 - (19%)
• Similarity: 250/704 - (35%)
• Gaps: 195/704 - (27%)

  Fly   105 EPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYK 169
            :||.:||.:.|.   ...|:.:..         ..:.|..||:...|:..:.|   .:|.| .:|
  Fly    44 QPCQDFYGYVCS---HSANLSETG---------RQRFQSLLKETDVAQLMDME---LQLIN-FFK 92

  Fly   170 ACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNA----DDSWTWQEQVKKFRTAGFSMDYIID 230
            :|.:...:|.|....:.|   :.||||.::.:..||    :.:..|...:..|...|  ..|..:
  Fly    93 SCESGRGVEALKGSQLYR---QSGGWPSLEPNKVNASQRTNQTQRWLGLLGYFHEVG--APYFFE 152

  Fly   231 FSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELL- 294
            .|:   ...|.|||:.|...           |.....:..:.:.:.::...||..:..|....|
  Fly   153 TSV---TMQSNKRLVVLQPD-----------GTRRNTLRKFEQRVGEVLQSFGIEQSRAHVTALE 203

  Fly   295 -LSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMIN 358
             ||||            ..||:..:..::..  |:|.:|...:.:.:.||           .:|.
  Fly   204 VLSLE------------RSRRDIVKADHVED--QVQFSYGNFKRIVFGNA-----------SLIR 243

  Fly   359 LSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQL-----QYATALSGRQEQE 418
            |....:|..|  |..|||:                  .|:....:||     .:|...:....:.
  Fly   244 LDWDGYFRKL--LGGKTPQ------------------ASDTIVVKQLPRLVEYFALLQNTSMVRL 288

  Fly   419 ARWKECVDIATSSMDEVCEDDFDSLGIS-VGSLYVGKHFHKDSKANALE---MVNEIRNVFNDIL 479
            ..|     |.|..:.::.:.|...|..: .|.||.  |..:...||.:|   |.:|:...:.|.|
  Fly   289 LNW-----IWTDYLMDIVDADCHQLSETYAGDLYA--HVVQRVTANRVELAQMYSELGKAYTDQL 346

  Fly   480 DEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKL--------DIDPDKYFESFLG 536
            ....|:|..:::.::..|.::.......||.||    |||::.|        :::..:.|:....
  Fly   347 GGSVWIDEISRQSSRQFLGNIMHTTLNGDERLD----AAYHSILLGRRSLYRNLEKLRKFQRTRR 407

  Fly   537 MNIFGTDYSFNKLRLPVNKTDWVRHARP-AIVNAFYSSLENSIQFPAG-ILQGHFFNAQRPKYMN 599
            :    ..:|..::|         |:|:. |.||||..  ::::..|.. :|.|.||:      .:
  Fly   408 L----ASHSAQQVR---------RYAQMFAPVNAFLG--QHNLSTPLNYLLLGEFFS------RS 451

  Fly   600 FGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATGLNLN 664
            ..|.|   ....|.|               .|...|:::.:....:|:            |...|
  Fly   452 LVAAG---SSSRTQG---------------AWRSSDSERRFAIFQQCV------------GKQTN 486

  Fly   665 GINTQGENIADNGGVKESYIAYRRW-AEKHGPEAKLPGLDYTPEQMFWVAAGQTWCAKYRKESLK 728
            .|:.....:|.    :::..||.:| |.:.|...::..:         :|||.   :|...:.|.
  Fly   487 AIDLLLSLLAQ----RQALSAYGQWLATQAGLVERVDAV---------LAAGS---SKMSLQRLF 535

  Fly   729 MRITTGVHSPSEFRVL----------GSLSNMKDFAKDFHCPEGSPMNPV-QKC 771
            ...:..|...||...|          .:|.|..:|.:.|.|..|..:.|. |:|
  Fly   536 FVTSLLVDCRSELGALQQDRKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRC 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	138/704 (20%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	137/701 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910