Protein Alignment Nep2 and Nepl6

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 755
• Identity: 150/755 - (19%)
• Similarity: 276/755 - (36%)
• Gaps: 204/755 - (27%)

  Fly    94 STVLRKMKPEVEPCDNFYEFACGTY-LEEENIP--------DDKVSISTFSVISDKLQEQLKDII 149
            :.:|..:..:...|..::::|||.| :...:.|        |.||:.:...::.:..|.......
  Fly    31 NNILSYVAEDSSACGTYFQYACGKYAVRHRDDPFTEIIQMLDHKVNGNLVQLMHELHQRSQSPGF 95

  Fly   150 TAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAE---RLG------GWP--LIKGDSW 203
            .....|.:..||      |:.|..        ..|.||..|   ||.      .||  :.:|:.|
  Fly    96 NESSVEAKVLHF------YRTCRE--------APPSTRKMEHYLRLAPPGQALTWPQFMPRGEPW 146

  Fly   204 NADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLV 268
             ....:.|.:.:......||: :.:::..:....:||.:..:|:...||....::| .||..||.
  Fly   147 -PKAQFKWMKSLGHLYRYGFT-NVLVNVLVLRSSENSNRFRLDISMPSLEGDAQHL-GGFLSTLA 208

  Fly   269 TAYYKYMVDIAVLFGANRDLAKTELLLSL-----EFEMALANISWPNEKRRNSSELYNLRTPAQL 328
            |..         :.|     ..|:.:|.|     ..|.|:..::..::.  :.||.:.||   |.
  Fly   209 TLQ---------IIG-----VPTKSILPLVRKIRRLESAIRVLTEVDDD--DESETWTLR---QW 254

  Fly   329 QAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSV 393
            :....|. |..::.:::  |.:|:...::......:|..|.:|:..|...|:|||:..|.    |
  Fly   255 EYKTGYA-WQGFVESIV--GHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRF----V 312

  Fly   394 GFLSEEF-------------------------RKRQLQYATALSGRQE-----QEARWKECVDI- 427
            .:|.::|                         ::|.|..||.....||     ::.|.:..:.|
  Fly   313 LYLIDDFIDSNEHIDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQIN 377

  Fly   428 -----ATSSMDEVCEDDFDSLGISVGSL--------YVGKHFHKDSKANALEMVNEIRNVFNDIL 479
                 .||..:.:.......:.:::|:|        :|.:|:.        ::|..:.: |:...
  Fly   378 ENRLGLTSEQNSMVATKAQHVVLNIGNLPRGRDHRSFVSRHYE--------DLVFPLPD-FDYAR 433

  Fly   480 DEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDY 544
            :.:|.::.:|:|:. |:|:..|.   .|||.        :|..   ||.....|
  Fly   434 EHLNLLEFRTRKQV-LQLNQSAP---TPDEF--------FYLS---DPKTAMSS----------- 472

  Fly   545 SFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGH 609
                                   ..:|....|.|..|.|:||..||.|.......:..:|:|:.|
  Fly   473 -----------------------GPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYSLLGFVLAH 514

  Fly   610 EITHGFDDQGRQFDVKGNLRDWWHPDTQKA--YLAKAKCIIEQYGNYTERATGLNLNGINTQGEN 672
            |:.|..|..|..:|..||:.: ..|....:  ::|..:|              ||.|......|.
  Fly   515 ELMHSVDTVGLYYDRYGNIHE-IGPQISSSPRFVAGLQC--------------LNRNSTQYLDER 564

  Fly   673 IADNGGVKESYIAYRRWAEKHGPEAKLPGLDYT---PEQMFWVAAGQTWCAKYRKESLKMRITTG 734
            |||..|:..:|..|.:      ..:::...|:|   |:|:|::...|.:|.....      |...
  Fly   565 IADIAGLDLAYSTYFQ------NSSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDP------INFV 617

  Fly   735 VHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774
            .|...|.|:...|:....|.:.|.||..|  |..:||::|
  Fly   618 GHDNDETRLQQMLNGFAPFHEAFGCPAKS--NQPEKCQLW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	147/741 (20%)
Nepl6	NP_609023.3	M13	47..653	CDD:341056	146/735 (20%)