Protein Alignment Nep2 and Nepl5

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 143/745 - (19%)
• Similarity: 274/745 - (36%)
• Gaps: 174/745 - (23%)

  Fly   100 MKPEVEPCDNFYEFACGTY----LEEENIPD------------DKVSISTFSVISDKLQEQLKDI 148
            |..:..||:|||::|||.:    .|:.::.|            ..:...|..:|...:..:|:.:
  Fly    44 MDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHSVNRKLELL 108

  Fly   149 ITAERP---ETEPKHFRLPNLLYKACMN------KTLIETLGPEPITRVAERLGGWPLIKGDSWN 204
            :.....   |::........|.|::|..      |..::.|.|...|:       ||.: |..|.
  Fly   109 LRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLLPPSNSTQ-------WPSV-GRGWR 165

  Fly   205 ADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVT 269
             .:.:.|...:.:.|..|.:         ||.|:.......| |..:.::   |:.|...:....
  Fly   166 -PERFDWITTLGRLRLHGLN---------GVLLREEVLPRWD-DSRNYSI---YVNKPSRQETQP 216

  Fly   270 AYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAY-- 332
            .....|:::.:..|..:..|........:||..|..:          .||.:...|.::|..|
  Fly   217 MGEGAMIELLLDIGQTKRTANALARQVDDFERKLHRL----------QELEDDEGPREMQLGYLD 271

  Fly   333 ---PYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMF--WRIHGFS 392
               |.::|:.:|..:..:........:|..::| :...|..|:.......:.:|:.  |
  Fly   272 SYLPQLRWLSFMRQVRIDSELDLRSTLIIENIP-YLRALSDLMESESPDTVCSYIMLKW------ 329

  Fly   393 VGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHF- 456
            :.||.        |...|...|.|..|..:..:.:|:|.:                   ||:.|
  Fly   330 LAFLK--------QQGPADISRGECVAALRRAMPLASSWL-------------------VGQQFS 367

  Fly   457 HKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKL--KLHSMATHIGY--PDEMLDNEKLA 517
            ..:|::....:...::..|..||.| |.|.........|  ||.::...:|:  .:|:.|.|:
  Fly   368 DPESESYVSSLFQRLKVRFGQILAE-NRMRLSPPLVHILQQKLRAVRLQMGFFQTEEIEDVEQ-- 429

  Fly   518 AYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLR-------LPVNKTDWVRHA-----------RP 564
             |:.::|:.         |.:.:|......:.|       |.:|.|::....           ..
  Fly   430 -YHVRIDLS---------GHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEA 484

  Fly   565 AIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLR 629
            :..:..|....|.:..|.|:||...::...........:|:|:.||:.||||..|..:|..||:.
  Fly   485 SNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGFDMLGMDYDAMGNIM 549

  Fly   630 DWWHPDTQKAYLAKAKCIIEQYGNYTERATGLN------LNGINTQGENIADNGGVKESYIAYRR 688
            .   |             :|:.|...:...||.      ..|.....|.:||...::.:|..:..
  Fly   550 G---P-------------VEEIGASRQFRQGLQCLQQQMATGSKWIDEKLADFVALRLAYETFFG 598

  Fly   689 WAEKHGP-EAKLPGLDYTPEQMFWVAAGQTWCAKY-----RKES---LKMRITTGVHSPSEFRVL 744
            ..:|..| :..||  .::..|:|::...|.:|.:.     |.:|   ||       |:..|.||:
  Fly   599 VRDKREPRDPLLP--QFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLK-------HAADELRVM 654

  Fly   745 GSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774
            .:|:|.::|:::|.|.:.:.|...|:|.:|
  Fly   655 QTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	140/737 (19%)
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	142/743 (19%)
		GluZincin	48..682	CDD:301352	140/737 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920