Protein Alignment Nep2 and Nep3

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 792
• Identity: 278/792 - (35%)
• Similarity: 430/792 - (54%)
• Gaps: 74/792 - (9%)

  Fly    10 W-WRRRNKLEKSLLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQAT--ALH-----GDSTTINQ 66
            | ||.|||.||.||::   .||:..|.|.|.|  ||.|...|: .||  .||     .|..:.|:
  Fly    42 WNWRSRNKTEKWLLIT---TFVMAITIFTLLI--VLFTDGGSS-DATKHVLHVQPHQKDCPSGNE 100

  Fly    67 VPTGTASKGKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSI 131
            :|               ||.:.||..:|.:|:.:...|:|||:||.::|..:::...||:.|.:.
  Fly   101 LP---------------CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTW 150

  Fly   132 STFSVISDKLQEQLKDIITAERPETEPKHF-----RLPNLLYKACMN-KTLIETLGPEPITRVAE 190
            .||..:     ||:..:|.....|...|.|     |...:.|::|:: ...:|.||.:|:..:..
  Fly   151 GTFGKL-----EQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLL 210

  Fly   191 RLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLAL- 254
            ::|||.:.| ..:|. .:||....:|..... ::.:.:..::||.|.:||::.:|.:||..|.|
  Fly   211 QIGGWNVTK-SGYNV-ANWTMGHTLKILHNK-YNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLP 272

  Fly   255 SREYLVKGFNET-----LVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRR 314
            :.:|.   .|:|     ::..|.:||..:.||.|||...|:.:::..:.||..||||:.|.|.||
  Fly   273 TADYY---NNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRR 334

  Fly   315 NSSELYNLRTPAQLQAAYPYVQWVDYM-NALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTP-- 376
            |...:|:.....||....|::.|.|:. ||:...|..|.:||::.:..|.|.::|..::.|..
  Fly   335 NEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQT 399

  Fly   377 ---KRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCED 438
               |..:.||:.|:........||:.||........||.|....|..|:.||           .|
  Fly   400 EEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCV-----------SD 453

  Fly   439 DFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATH 503
            ..:.:|.:||:::|.:.||.:||..|.:|:.|||..|...|..:.|:|.:|:::|..|.:.::..
  Fly   454 TNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDM 518

  Fly   504 IGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVN 568
            ||:||.:||..:|...||:|:|.|:.|||:.:.:.|:....:..:|..|||||:|  ...|..||
  Fly   519 IGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNW--GMTPQTVN 581

  Fly   569 AFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWH 633
            |:|:..:|.|.|||||||..||:...||.:||||:|.|:|||:||.||||||::|..||:..||.
  Fly   582 AYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWD 646

  Fly   634 PDTQKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRW-AEKHGPEA 697
            ..:.:.:..|::||..||..|  :..|..|||..|.|||||||||:|.:|.||:|. :::.....
  Fly   647 SKSIERFNEKSECIARQYSGY--KMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDIL 709

  Fly   698 KLPGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEG 762
            |||||:.|..|:|:|:..|.||:....|:..:::....||||:|||:|:|||||:||:.|.|..|
  Fly   710 KLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPG 774

  Fly   763 SPMNPVQKCEVW 774
            ..|||.:|||||
  Fly   775 KRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	241/686 (35%)
Nep3	NP_523417.2	M13	123..784	CDD:341056	241/686 (35%)