Protein Alignment Nep2 and frma

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 152/738 - (20%)
• Similarity: 274/738 - (37%)
• Gaps: 208/738 - (28%)

  Fly    99 KMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKL----QEQLKDIITAERPETEPK 159
            |..|:.:||.|||:.|||.:....       :..::....|:|    ||:|.|::..||.:.||
  Fly    20 KSHPQADPCQNFYKVACGNWSASH-------ATDSYESFMDRLDYNYQEKLADLLDNEREDDEP- 76

  Fly   160 HF--RLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAG 222
            ||  :|.| .|.||.     :.|..:.:.|:.|.|    ::..:..|        |::....||.
  Fly    77 HFLQQLRN-FYTACR-----KPLSQDQVLRILEHL----IVMENIQN--------EELSVGLTAA 123

  Fly   223 FSMDYIID------FSIGVDLQNSTKRLIDLDQSSLALSREYLVK----------GFNETLVTAY 271
            |.:..:||      :.|...|.:..|.......:...|:||...|          .|.|     |
  Fly   124 FRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPFPFKE-----Y 183

  Fly   272 YKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPY-- 334
            |.            |:|::.|..:          :|:.:|.....|.....|.|       |:
  Fly   184 YW------------RELSELEEKI----------MSYGSEDDGFDSGDLVTRIP-------PFWM 219

  Fly   335 VQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEE 399
            :.|        |.| |:..:   |||..:.:.|:      .....|..|::.|:...:.|..:|.
  Fly   220 MPW--------PNG-NITYE---NLSQMAHWLDI------KANEFILTYIYMRLKLVAEGVSTES 266

  Fly   400 F---------RKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKH 455
            :         :.||:....|....::...|.||         :.|.:|.|..|         .:.
  Fly   267 WHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKE---------EPVLQDIFAEL---------KQR 313

  Fly   456 FHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYY 520
            |.:...||   ..|..|:..:.:|.::        |..:|:| |:.........|:  .::..:|
  Fly   314 FGQKLLAN---RNNFTRSTQHFLLGKL--------KRMRLRL-SILPRNSSAQSMV--RRIERHY 364

  Fly   521 AKLDIDPDKYFESF-LGMN--------------IFGTDYSFNKLRLP--VNKTD----WVRHARP 564
            ..:.::...||.:. :|:|              :||      :..:|  ::|:|    .|| ...
  Fly   365 RDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFG------RQLIPSRISKSDLYPTQVR-GYG 422

  Fly   565 AIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKG--- 626
            ...:|||...:|.:..|..:|:..|:...:|..:.:.|:|:::|||::||||.:|..|...|
  Fly   423 TYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGS 487

  Fly   627 -----NLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAY 686
                 .|      |....:..:..|:..::|              ..:.|..||..|::.:|.||
  Fly   488 SAVDREL------DRNPRFQQELGCLRRRFG--------------RKRYEKFADASGLELAYSAY 532

  Fly   687 RRWAEKHGPEAKLPGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMK 751
            ...|:......:......|.:|.|:....|.:|:.  ||.|:..    .|.....||..::::.:
  Fly   533 FDTAQTDHKRNRSAEELVTQKQQFFHNFAQFFCSD--KELLQAH----DHGSDRKRVNDAVAHFE 591

  Fly   752 DFAKDFHCPEGSPMNPVQKCEVW 774
            .|.:.|.|   .|....::|.::
  Fly   592 PFREAFSC---GPSPRRRQCRLY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	149/729 (20%)
frma	NP_572226.2	GluZincin	25..601	CDD:301352	148/721 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010