Protein Alignment Nep2 and nep-25

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_495164.2
• Gene: nep-25 / 191543
• WormBaseID: WBGene00022874
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 105/491 - (21%)
• Similarity: 179/491 - (36%)
• Gaps: 130/491 - (26%)

  Fly   364 FFEDLGKLLAKTPKRVIANY-----MFWRIHGFSVGFLSEEFRKRQLQYATA--------LSG-- 413
            |.|||.||.|    .::|.|     .|.:..|.....::|..::..::...:        ||.
 Worm    59 FMEDLSKLKA----GMVAKYRKKHPKFDKFKGEDAFAIAEALKQLNIEQLKSECKPSKPRLSSFF 119

  Fly   414 RQEQEARWKE--------------CVDIATSSMDEVCE-DDFDS----LGISVGSLYVGKHFHK- 458
            ...|:.|..|              |.:.|...:.||.| :|:.:    |..:|......|...|
 Worm   120 ISAQDNRTIENVDEVLFPGFENYPCEEKAAIIIKEVGEIEDYTTTRSVLVSAVNGFITSKLVEKL 184

  Fly   459 DSKANALEMVNEIRNVFNDILDEVNWMDAKTKK--EAKLKLHSMATHIGYPDEMLDNEKLAAYY- 520
            |.||.  ::.|:.::|.:..:.:..|  ||..|  |..::..|..|...:.|..:..:|....|
 Worm   185 DVKAR--KLFNKFKSVISKEIIKTPW--AKNYKAIEQYVEALSNITFRTFADVRITVKKSMELYE 245

  Fly   521 -------AKLDI---DP------------------DKYFESFLGMNIFGTDYSFNKLRLPVNKTD 557
                   .|||:   .|                  |:..|     :||..|      :..:.|..
 Worm   246 STEKDCRKKLDVAFSQPTAELVCKGVATRKAEELLDEPIE-----DIFPQD------QAGILKDV 299

  Fly   558 WVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMN--FGAIGYVIGHEITHG--FDDQ 618
            |          ..::|.:||:     .:...|.......|.:  :|:||:.:.|||.|.  |||.
 Worm   300 W----------QMFNSFDNSV-----YIGNEFLLLLNTDYFSDLYGSIGFSMIHEIMHTLVFDDN 349

  Fly   619 GRQFDVKGNLRDWWHPDTQKAYLAKAKCI--IEQYGNYTERATGLNL----NGINTQGENIADNG 677
                |:...|...|   |:.|...|.:.:  .|.:...||..   |:    |...|..|:.||..
 Worm   350 ----DLDKPLSKLW---TKNADCVKDQALKTCETFPTVTEMH---NMKPACNTTVTFEEDAADLA 404

  Fly   678 GVKESYIAYRRWAEKHGPEAKLPGLD-YTPEQMFWVAAGQTWCAKYRKESL-KMRITTGVHSPSE 740
            ..:   ||:|.:...:..:..:|..: ...:|:|:..|...:|   .::.: ::......||.:.
 Worm   405 AYR---IAWRIYENSYARKTVVPNYEALDKKQLFFYGAAVFFC---NQDGMSRVPFQNLAHSNNY 463

  Fly   741 FRVLGSLSNMKDFAKDFHCPEGSPM--NPVQKCEVW 774
            .||...:|.||.|:..|.|.....|  |..:.||::
 Worm   464 QRVNSLMSQMKQFSDAFKCKPTDKMITNRAKHCELY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	103/487 (21%)
nep-25	NP_495164.2	Peptidase_M13	308..496	CDD:279739	49/208 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000