Protein Alignment Nep2 and nep-4

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_509156.2
• Gene: nep-4 / 183746
• WormBaseID: WBGene00016896
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 107/595 - (17%)
• Similarity: 199/595 - (33%)
• Gaps: 229/595 - (38%)

  Fly   226 DYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAK 290
            ::..||     ::|:.::::|                :.......:|::...:    |:..|:.|
 Worm    17 EHPFDF-----IENALEKIVD----------------WKSDPCDDFYRHACPV----GSIEDIIK 56

  Fly   291 TELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDE 355
                :|::......|.||..:.:||..::||
 Worm    57 ----VSMQPLKDALNHSWKQKGQRNEGKVYN---------------------------------- 83

  Fly   356 MINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEAR 420
             ||..                :..|..:.|.::.     |:..:::.|.:.|.|...|..:
 Worm    84 -INFR----------------RSHICCHFFCKLL-----FIYYDYQYRFINYVTFYDGMLQ---- 122

  Fly   421 WKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVN-W 484
                                        .||    :|.:  ||..:.:|||..:..|:::..| |
 Worm   123 ----------------------------PLY----YHVE--ANVTDGINEIHQMMEDMVELGNIW 153

  Fly   485 MDAKTKKEAKLKLHSMATHIGYP----DEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYS 545
            :: ||                 |    :.:.:..|......|:.:...||           |::.
 Worm   154 LE-KT-----------------PWVINNNLTEEMKNITNAIKMPVSLTKY-----------TNFI 189

  Fly   546 FNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQF----PAGIL---QGHFF------NAQRPKY 597
            :|.|. |: :||::.     .|:.| ..::|:..|    .|.|.   :|.:|      ||:...|
 Worm   190 YNLLS-PI-ETDFLN-----CVSEF-EGIQNNTLFCLFYSAKIFVRTRGSYFIDDNGYNAEGTIY 246

  Fly   598 MNF-------------GAIGYV---IGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAK- 645
            ..|             ..:||.   :||||.|.|.:..            .:||....:...|:
 Worm   247 FGFPNYYHTTYGNWRASKLGYTGTRVGHEIGHTFIEHS------------INPDGLPYFSKPAED 299

  Fly   646 CIIEQY----GNYTERATGLNLNGINTQGENIADNG----GVKESY-IAYRRWAEKHGPEAKLPG 701
            |:..||    ..|.|   |...:..||......|||    |::.:| |..|..:::...:|  .|
 Worm   300 CVQNQYLKTCNEYYE---GEVPDACNTSDYTFDDNGADVFGLQLAYAILERDLSDQLREQA--DG 359

  Fly   702 LDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPM- 765
            |..|.||:.:.:....:|     ...|...|.|.||....|: .:::.|..|.:.|:|...|.|
 Worm   360 LKITNEQLLFYSFAYRFC-----RGSKSNTTDGSHSHHNVRI-NAVAQMPGFQQAFNCASDSRMM 418

  Fly   766 -NPVQKCEVW 774
             :..::|.::
 Worm   419 KSATKQCVIY 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	106/591 (18%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:472708	45/197 (23%)