Protein Alignment Nep2 and Nep3

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_317711.2
• Gene: Nep3 / 1278166
• VectorBaseID: AGAMI1_011685
• Length: 789
• Species: Anopheles gambiae
• Alignment Length: 781
• Identity: 274/781 - (35%)
• Similarity: 421/781 - (53%)
• Gaps: 56/781 - (7%)

  Fly    11 WRRRNKLEKSL--LVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGDSTTINQVPTGTAS 73
            |..|:||||.|  |::|.|:.:|:.                    ::.|..|:|.|..|.....|
Mosquito    48 WNARSKLEKVLLSLLALSIILIVVL--------------------SSLLASDTTRILHVRPHVGS 92

  Fly    74 KGKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVIS 138
            .....|....||.|.||..||.:|..:...|:|||:||.|:|..::....||:.|.....|..:.
Mosquito    93 DPFGVDEQLPCLNQHCIFAASEILHSIDWSVDPCDDFYAFSCNQWIRNNPIPEGKSMWGLFGKLE 157

  Fly   139 DKLQEQLKDIITAERP--ETEPKHFRLPNLLYKACMNK-TLIETLGPEPITRVAERLGGWPLIKG 200
            .:.|..||:.:  |||  |.:.|..:...|.|::|::: ..:|.||.||:.::..::|||.:...
Mosquito   158 QQNQLVLKNAL--ERPLAEFKSKAEKKAKLYYQSCLDEDETMEKLGAEPLQKLLRQIGGWNVTAN 220

  Fly   201 DSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLAL-SRE-YLVKGF 263
            .|......|:.|..::..:.. ::|..:..:::|.|.:||:|.:|.:||..|.| ||: ||.|..
Mosquito   221 ASGFDVQRWSLQRTLQTLQIR-YNMGGLFGWAVGEDDRNSSKHIIQIDQGGLTLPSRDNYLNKTA 284

  Fly   264 NETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQL 328
            |..::|||.:||..::||.||:...|:.::|..:|||..||||:.|.:.||:...||:..|.|.|
Mosquito   285 NAKILTAYLEYMTKVSVLLGADETDARRQMLEVIEFETRLANITTPQDMRRDEETLYHPMTLAML 349

  Fly   329 QAAYPYVQWVDYM-NALLPEGLNVAEDEMINLSVPSFFEDLGKLLAK-----TPKRVIANYMFWR 387
            |...|::.|.::. .|.......:.|.|.:.:..|.:.|.|..|:.:     ..|.::.||:.|:
Mosquito   350 QEKAPFINWQEHFEEAFRLVRRKITEKERVVVYAPEYLEKLNILMKEYTSTDEKKIILNNYLVWQ 414

  Fly   388 IHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYV 452
            ........||:.||........||.|....|..|:.||           .|..:.||.:||:::|
Mosquito   415 TVRTLTACLSKAFRDAYKGLRKALMGSDGGEELWRYCV-----------SDTSNVLGFAVGAMFV 468

  Fly   453 GKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLA 517
            ...||.|||..|.||:|::|:.|.:....:.||||:|::.|..|..:::..||:||.:|..|:|.
Mosquito   469 RDVFHGDSKPQAEEMINQVRDAFKENFKNLGWMDAETRRLAVEKADAISDMIGFPDYILYPEELD 533

  Fly   518 AYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPA 582
            ..|..|:|||..||::.:..||:....:..||..|||||.|  ...|..|||:|:..:|.|.|||
Mosquito   534 RKYQDLNIDPKTYFDNNINYNIYSLKKNLEKLDQPVNKTKW--GMTPPTVNAYYTPTKNQIVFPA 596

  Fly   583 GILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCI 647
            ||||..||:.:..|.:|:||:|.|:|||:||.||||||::|..|||..||:..|.:.:..:.:|.
Mosquito   597 GILQNPFFDIKNSKSLNYGAMGVVMGHELTHAFDDQGREYDKYGNLHQWWNNQTIERFKNQTECF 661

  Fly   648 IEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHG----PEAKLPGLDYTPEQ 708
            .:||..|  |..|..:||..|.|||||||||:|.::.||.. .||:.    ....|||::.|..|
Mosquito   662 NQQYSAY--RINGKTINGKQTMGENIADNGGLKAAFHAYIN-NEKNSYTDTDTLPLPGVNMTHRQ 723

  Fly   709 MFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEV 773
            :|:|:..|.||:....|:..::|....|||.::||:|.|||:|:|:..||||.|:.|||::||.|
Mosquito   724 LFFVSFAQVWCSAVTDETTTLQIEKDSHSPPKYRVIGPLSNLKEFSDTFHCPLGTGMNPIEKCVV 788

  Fly   774 W 774
            |
Mosquito   789 W 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	245/682 (36%)
Nep3	XP_317711.2	None