Protein Alignment Nep2 and Eef1ece2

DIOPT Version :10

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_808810.1
• Gene: Eef1ece2 / 110599584
• MGIID: 6121518
• Length: 910
• Species: Mus musculus
• Alignment Length: 764
• Identity: 257/764 - (33%)
• Similarity: 404/764 - (52%)
• Gaps: 72/764 - (9%)

  Fly    22 LVSLGIMFVVLATGFG----LWIGKVLRTSPPSNPQATALHGDSTTINQVPTGTASKGKSGDSGD 82
            ||..|::.|:.|...|    ||:                 |.|                  .:..
Mouse   208 LVLAGLILVLAALLLGCLVALWV-----------------HRD------------------PAHS 237

  Fly    83 VCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKD 147
            .|:|:.||..|..:|..:...|.||.:||:|:||.::....:|:.:...:||:.:.|:.|..||.
Mouse   238 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKH 302

  Fly   148 IITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQ 212
            ::......:..:..|.....|.:|:....||.||.:|:..:.:::|||.:.  ..|:.|   ::.
Mouse   303 LLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNIT--GPWDED---SFM 362

  Fly   213 EQVK----KFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLAL-SRE-YLVKGFNETLVTAY 271
            :.:|    .:|...|...|     :..|.::|...:|.:|||.|.| ||: ||.:..||.::|||
Mouse   363 DVLKAVAGTYRATPFFTVY-----VSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAY 422

  Fly   272 YKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQ 336
            ..|||::.||.|......:.::...||.|:.||||:.|.::||:..::|:..:.::|||..|.|.
Mouse   423 LDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVD 487

  Fly   337 WVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFR 401
            |:::::.|| ..|.:.:.|.:.:....:.:.:.:|:.:|...::.||:.|.:...:...|.:.|.
Mouse   488 WLEFLSFLL-SPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFE 551

  Fly   402 KRQLQYATALSGRQEQ-EARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANAL 465
            ..|.:....|.|.::. ..||:.|:    |:.|       |:||.::|||:|...|.:.||..|.
Mouse   552 TAQEKLLETLYGTKKSCTPRWQTCI----SNTD-------DALGFALGSLFVKATFDRQSKEIAE 605

  Fly   466 EMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKY 530
            .|:||||:.|.:.|.::.|||.||:..||.|..::...||:||.:|:.::|...|...::..|.:
Mouse   606 GMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSF 670

  Fly   531 FESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRP 595
            |::.|.:..|......::||.|.::..|  ...|..|||:|...:|.|.|||||||..|:....|
Mouse   671 FQNMLNLYNFSAKVMADQLRKPPSRDQW--SMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHP 733

  Fly   596 KYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATG 660
            |.:|||.||.|:|||:||.||||||::|.:||||.||..::..|:.....|:.|||..|  :..|
Mouse   734 KALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQY--QVNG 796

  Fly   661 LNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPEAKLPGLDYTPEQMFWVAAGQTWCAKYRKE 725
            ..|||:.|.|||||||||:|.:|.||:.|..|||.|..||.:..|..|:|:|...|.||:....|
Mouse   797 ERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPE 861

  Fly   726 SLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774
            |....:.|..|||:.|||||:|||.:||.:.|.||.||||||.|.||||
Mouse   862 SSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:341056	237/674 (35%)
Eef1ece2	NP_808810.1	UbiG	46..>128	CDD:441829
		M13	259..908	CDD:341056	237/674 (35%)