Protein Alignment Nep2 and ecel1

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 783
• Identity: 249/783 - (31%)
• Similarity: 398/783 - (50%)
• Gaps: 82/783 - (10%)

  Fly     8 PNWWRRRNKLEKSLLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQ-ATALHGDSTTINQVPTGT 71
            |.|.||...|...|:.::|:..:         :|.:|.....|..| ...|.|
 Frog    48 PRWSRRETCLLSGLVFAVGLCVI---------LGCMLVLKYLSMEQDVQCLEG------------ 91

  Fly    72 ASKGKSGDSGDVCLTQECIHTAST-VLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFS 135
                        |..::....||. :...:.|.:.||.:||.||||.:|....||:||:...|.:
 Frog    92 ------------CQERKAFMRASKFITNNIDPTISPCTDFYSFACGGWLRRHGIPEDKLIYGTIA 144

  Fly   136 VISDKLQEQLKDII----------TAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAE 190
            .|.::.:|:|:.::          :|||...|         .:|:|:|...|:.||..|:.:|.|
 Frog   145 AIGEQNEEKLEHLLLQPVRRKHKGSAERKVKE---------FFKSCLNMRDIDRLGARPMLQVIE 200

  Fly   191 RLGGWPLIKGDSWNADDSWTWQEQVKKFRTAG-FSMDYIIDFSIGVDLQNSTKRLIDLDQSSLAL 254
            ..|||.|.:      |....|......::|.| :|.......::.:|.:||::.:|.:||..|.|
 Frog   201 DCGGWDLPE------DPRTQWDFNELLYKTQGVYSTAVFFSMTVSLDDKNSSRYIIRIDQDGLTL 259

  Fly   255 SREYLVKGFNE---TLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNS 316
            ....|..|.:|   .::.||..:|..|..|.|......|.|.:|.||..::...||..::.||:.
 Frog   260 PERTLYLGQDEESIKVLEAYKVFMQTILSLLGVENVQKKAEEILHLEQHLSNITISEFDDMRRDI 324

  Fly   317 SELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIA 381
            |.:||..|.||||...|::.|.:.:|.:.  ..|..|||.:.:....:.:.:.:::..||..|:.
 Frog   325 STMYNKVTLAQLQQITPHLNWKNLLNRIF--HTNFPEDEEVVVLATDYMQKVSEMIRSTPASVLH 387

  Fly   382 NYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGIS 446
            |||.|||.......||..||....:.:..:.|.::|....|.|:..|..           ..|::
 Frog   388 NYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGSEKQAELTKVCLTQANK-----------HFGMA 441

  Fly   447 VGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEML 511
            :|:|:|.::|...|||...::|..|:::.:..|:|::|||.:||:.|:.||..|...|||||.:|
 Frog   442 LGALFVEEYFSSSSKAKVQQLVENIKHILDYRLEELDWMDTETKQAAREKLKHMMVMIGYPDVLL 506

  Fly   512 DNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLEN 576
            ..|.:...| :.:::...||::.|....:....:..::|..|:|:.|:  ..|..:||:|...:|
 Frog   507 QPESMDKEY-EFEVNEKTYFKNILNSIRYSIKMAVRRIRQEVDKSAWL--LPPQALNAYYLPNKN 568

  Fly   577 SIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYL 641
            .:.|||||||...::...|:.:|:|.||.:||||:|||:||.|.|:|..||...||..|:...:|
 Frog   569 QMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDANGNPIQWWTEDSYSKFL 633

  Fly   642 AKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPEAKLPGLDYTP 706
            .||:||::.|.|:|  .....:||..|.||||||.||:|.:|.||::|...:|||..||.|.||.
 Frog   634 KKAECIVDLYENFT--VYNQRVNGRTTLGENIADLGGLKLAYYAYQKWVRDNGPERPLPRLKYTH 696

  Fly   707 EQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKC 771
            :|:|::|..|.||.|.|.:|:.:::.|..|:|..:||:||:|..::|.:.||||..||||||.||
 Frog   697 DQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNSPMNPVHKC 761

  Fly   772 EVW 774
            .||
 Frog   762 SVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	229/681 (34%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	229/681 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61902
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030