Protein Alignment Nep2 and ece1

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_031762312.1
• Gene: ece1 / 100485607
• XenbaseID: XB-GENE-1014218
• Length: 782
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 267/779 - (34%)
• Similarity: 415/779 - (53%)
• Gaps: 83/779 - (10%)

  Fly    11 WRRRNKLEKSLLV-----SLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGDSTTINQVPTG 70
            |..|..:||.|||     |||:...:||...
 Frog    72 WAERTHVEKRLLVLVVLLSLGLFMCLLALSL---------------------------------- 102

  Fly    71 TASKGKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFS 135
                 :..:|..|||::.||...|::||.:....:||.:||:::||.:::...:||......||:
 Frog   103 -----QYRNSHRVCLSESCISVTSSILRSLDRSADPCQDFYQYSCGGWIKGNPVPDGHSRWGTFN 162

  Fly   136 VISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKG 200
            .:.:..|..:|.::.....||.....|.....::||||:|.||.||.:|:..:.::||||.:.
 Frog   163 ELWEHNQATMKHLLENSTIETNSTAERKAQRYFQACMNETKIEELGAKPLQDLIQKLGGWAIT-- 225

  Fly   201 DSWNADDSWTWQEQVK----KFRTAGFSMDYIIDFSIGV--DLQNSTKRLIDLDQSSLAL-SRE- 257
            ..|:.|:   :||.::    .:||:.|       ||:.|  |.:||...:|.:|||.|.| |||
 Frog   226 GPWDRDN---FQETLQLVTAHYRTSPF-------FSVFVSADSKNSNSNVIQIDQSGLGLPSREF 280

  Fly   258 YLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNL 322
            ||.|..||.::|.|..:|:.:.||.|...:..:.::...|:||..||||:.|.||||:..::|:.
 Frog   281 YLNKTENEKVLTGYLNFMIQLGVLLGGAENSTREQMQEILDFETTLANITIPQEKRRDEEQIYHK 345

  Fly   323 RTPAQLQAAYPYVQWVDYMNALL-PEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFW 386
            ....:|:...|.|.|:.::..:. |..:|  |.|.:.:....:...:..|:..|.||::.|||.|
 Frog   346 MAAGELKDLVPAVDWMPFLQTVFYPVAIN--ESEPVVVYAKEYLVAVSGLINSTDKRILNNYMMW 408

  Fly   387 RIHGFSVGFLSEEFRKRQLQYATALSGRQEQ-EARWKECVDIATSSMDEVCEDDFDSLGISVGSL 450
            .:...:..||.:.|:..:.:....:.|.::. ..|||.|:           .|..::||.::|::
 Frog   409 NLVRKASSFLDQRFQDAEEKLMEVMYGTKKTCLPRWKFCI-----------SDTDNNLGFALGAM 462

  Fly   451 YVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEK 515
            :|...|.::||..||:|:.||:..|.:.|..:.|||.:|::.|:.|..::...||||:.::|.::
 Frog   463 FVKATFAENSKLQALKMIKEIKAAFEENLSTLTWMDDETRRAAREKAEAIYDMIGYPNFIMDPKE 527

  Fly   516 LAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQF 580
            |...:...::..|.|||:.:....|....:.::||...:|..|  ...|..|||:||..:|.|.|
 Frog   528 LDKVFNDYNVTSDFYFENGMRFYNFSARVTADQLRKAPSKDQW--SMTPPTVNAYYSPTKNEIVF 590

  Fly   581 PAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAK 645
            ||||||..|:.:..|..:|||.||.|:|||:||.||||||::|..||||.||...:.:|:..:.:
 Frog   591 PAGILQAPFYTSSSPTALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNASVEAFKKQTE 655

  Fly   646 CIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPEAKLPGLDYTPEQMF 710
            ||.|||||||  ..|..:||..|.|||||||||:|.:|.||:.|..|:|.|..||.|..:.:|:|
 Frog   656 CITEQYGNYT--VNGEPVNGRQTLGENIADNGGLKAAYRAYKNWVRKNGAEQLLPSLGLSNDQLF 718

  Fly   711 WVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW 774
            :|...|.||:....||....:.|..||||.|||:||:||.::||:.|.||.||||||..|||||
 Frog   719 FVGFAQVWCSVRTSESSHEGLITDPHSPSRFRVIGSVSNSQEFAEHFRCPPGSPMNPRNKCEVW 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	242/677 (36%)
ece1	XP_031762312.1	M13	131..780	CDD:341056	242/677 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010