Protein Alignment Nep2 and LOC100332538

DIOPT Version :9

• Sequence 1: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_021322193.1
• Gene: LOC100332538 / 100332538
• -ID: -
• Length: 808
• Species: Danio rerio
• Alignment Length: 788
• Identity: 258/788 - (32%)
• Similarity: 407/788 - (51%)
• Gaps: 85/788 - (10%)

  Fly    11 WRRRNKLEKSLLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGDSTTINQVPTGTASKG 75
            |.||   |..||.:|     |.|.|..:.:|.:|                           |.|.
Zfish    82 WSRR---EICLLSAL-----VFAAGMCVILGCML---------------------------ALKF 111

  Fly    76 KSGDSGDVCLTQECI------HTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTF 134
            . ..|.|....|:|:      ..|..|...:.|.|:||.:||.||||.:|....||:||:|....
Zfish   112 LXARSQDSQCRQDCVKRRSLLRAARFVQGNIDPSVQPCHDFYSFACGGWLRRHGIPEDKLSYGII 176

  Fly   135 SVISDKLQEQLKDIITA-------ERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERL 192
            :.|.::.|::|:.::.|       |..|.:.|.|      |::|:|...|:.||..|:|.|.:..
Zfish   177 TAIGEQNQDKLQRLLQAPVQRRELESAERKVKEF------YRSCINIKEIDRLGAGPMTEVIDSC 235

  Fly   193 GGWPLIKG-------DSWNADDSWTWQEQVKKFRTAG-FSMDYIIDFSIGVDLQNSTKRLIDLDQ 249
            |||.|...       ||.:|.....:.|.:  ::|.| :|.......::.||.:||::..|.:||
Zfish   236 GGWDLSGAPPGGAGWDSGSAPIRPDFNEML--YKTQGVYSTSVFFSLTVSVDDKNSSRNAIRIDQ 298

  Fly   250 SSLALSREYLVKGFNE--TLVTAYYKYMVD-IAVLFGANRDLAKTELLLSLEFEMALANISWPNE 311
            ..|.|....|..|.:|  ..:.|.||.::: :..:.||:....|:..:|.||.::|...:|...:
Zfish   299 EGLTLPERTLYLGQDEDSVKILASYKALMERLLSMLGAHNATLKSREILDLETKLANITVSEYED 363

  Fly   312 KRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTP 376
            :|::.|.:||..|..|||...|...|...::.:..:  |.:|:|.|.:....:.:.:..::..|.
Zfish   364 QRKDISSMYNRITLKQLQKMAPSFHWKRLLDRIFND--NFSEEEEIVVLATDYMQTVSDIIKTTS 426

  Fly   377 KRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFD 441
            |||:.|||.||:.......||..||....:::..:.|.::|....:.|:..|..
Zfish   427 KRVLHNYMLWRMVAALSEHLSTAFRSTIHEFSREIDGTEQQLDLERLCLTQANK----------- 480

  Fly   442 SLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAKLKLHSMATHIGY 506
            ..|:::|:|:|.:||...|:|...|:|.:|::..:..|.|::|||.:||..|:.||..|....||
Zfish   481 HFGMALGALFVQQHFSSSSRAKVQELVEDIKHSLDVRLQELDWMDEETKDAARGKLQHMMVMTGY 545

  Fly   507 PDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARPAIVNAFY 571
            ||.:|..|.:...|| .|::...||::.|....:....|..|:...|:||.|:  ..|..:||:|
Zfish   546 PDFLLKPELIDEEYA-FDVNEKTYFKNILNSIKYNIKLSIKKIHKEVDKTTWL--LPPQALNAYY 607

  Fly   572 SSLENSIQFPAGILQGHFFNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDT 636
            ...:|.:.|||||||...::.:.|:.:|:|.||.:||||:|||:||.|.|:|..|||:.||..::
Zfish   608 LPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGAIIGHELTHGYDDWGGQYDRYGNLKQWWTEES 672

  Fly   637 QKAYLAKAKCIIEQYGNYTERATGLNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPEAKLPG 701
            .:.:..|.:||::.|.|:|  .....:||..|.||||||.||:|.||.||::|..:||||..|||
Zfish   673 YRKFQKKTECIVKLYDNFT--VYNQRVNGRLTLGENIADLGGLKLSYHAYQKWVREHGPERPLPG 735

  Fly   702 LDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMN 766
            |.:|.||:|::|..|.||.|.|.:|:.:::.|..|:|..:||:||:|..::|.:.||||.|||||
Zfish   736 LKHTHEQLFFIAFAQNWCMKRRSQSIYLQLLTDKHAPEHYRVIGSVSQFEEFGRVFHCPRGSPMN 800

  Fly   767 PVQKCEVW 774
            ||.||.||
Zfish   801 PVNKCSVW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep2	NP_001246914.1	M13	104..772	CDD:189000	234/685 (34%)
LOC100332538	XP_021322193.1	M13	146..806	CDD:189000	234/685 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61902
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100162
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830