Protein Alignment eIF3f1 and MPND

DIOPT Version :9

• Sequence 1: NP_649489.1
• Gene: eIF3f1 / 40587
• FlyBaseID: FBgn0037270
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001287791.1
• Gene: MPND / 84954
• HGNCID: 25934
• Length: 501
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 54/239 - (22%)
• Similarity: 88/239 - (36%)
• Gaps: 72/239 - (30%)

  Fly    13 VVLFQVVDAFERRNA----------DSH------RVIGTLLG--SVDKGVVEVTNCFCVPHKEHD 59
            |..|..::.|:..|.          |.|      .|:|.|.|  .|:..::.|...|....:..|
Human   258 VTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNSQMLTVLRAFPCRSRLGD 322

  Fly    60 DQ----VEAELSYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNNPVHLTVDT 120
            .:    :|.|:..:|.:..|        |:|||:        ||            :| |.....
Human   323 AETAAAIEEEIYQSLFLRGL--------SLVGWY--------HS------------HP-HSPALP 358

  Fly   121 SLQGGRMGLRAYVCIQLGVPGGKSGCMFTPIPVELTS--YE----PETFGLKLLQKTVGVSPAHR 179
            |||    .:.|.:..||.:.|..:|  |.|....|.|  |.    ||:   |:....|...|..|
Human   359 SLQ----DIDAQMDYQLRLQGSSNG--FQPCLALLCSPYYSGNPGPES---KISPFWVMPPPEQR 414

  Fly   180 PKT--VPPMLDLAQISEASTKLQSLLDLILKYVDDVIAHKVTPD 221
            |..  :|..:::|.:.::......|.:::|.    |..:|.:||
Human   415 PSDYGIPMDVEMAYVQDSFLTNDILHEMMLL----VEFYKGSPD 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	54/239 (23%)
MPND	NP_001287791.1	MPN_2A_DUB	266..450	CDD:163698	49/225 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900