DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and EIF2

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_181528.1	Gene:	EIF2 / 818587	AraportID:	AT2G39990	Length:	293	Species:	Arabidopsis thaliana

Alignment Length:	270	Identity:	105/270 - (38%)
Similarity:	158/270 - (58%)	Gaps:	10/270 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTVRVHPVVLFQVVDAFERRNADSHRVIGTLLGSV-DKGVVEVTNCFCVPHKEHDDQVEAELSYA 69
            ||.|:||:|:|.|.|.|.||...:.|||||||||: ..|.|::.|.:.|||.|..|||..::.|.
plant    26 LTARIHPLVIFNVCDCFVRRPDSAERVIGTLLGSILPDGTVDIRNSYAVPHNESSDQVAVDIDYH 90

  Fly    70 LDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLRAYVC 134
            .:|...:.||||.|::|||::||..|...||:||::||||..||:||||||....|...::|:|.
plant    91 HNMLASHLKVNSKETIVGWYSTGAGVNGGSSLIHDFYAREVPNPIHLTVDTGFTNGEGTIKAFVS 155

  Fly   135 IQLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQISEASTKL 199
            ..|.:...:....|..|||:|...:.|..|..:|:.|   |....|.      ||..:.....:|
plant   156 SNLSLGDRQLVAHFQEIPVDLRMVDAERVGFDVLKAT---SVDKLPN------DLEGMELTMERL 211

  Fly   200 QSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRNLLLVITLSQLI 264
            .:|::.:.||||.|:..::.|||.:||.:.|.:.|:|.:..:.|..:.|.::::.||::.||.:.
plant   212 LTLINDVYKYVDSVVGGQIAPDNNIGRFIADAVASLPKLPPQVFDNLVNDSLQDQLLLLYLSSIT 276

  Fly   265 KTQLQLNEKL 274
            :|||.|.|||
plant   277 RTQLSLAEKL 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	101/266 (38%)
EIF2	NP_181528.1	MPN_eIF3f	29..286	CDD:163695	101/265 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I2137
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2783
Inparanoid	1	1.050	192	1.000	Inparanoid score	I1369
OMA	1	1.010	-	-		QHG54712
OrthoDB	1	1.010	-	-		D1038775at2759
OrthoFinder	1	1.000	-	-		FOG0004972
OrthoInspector	1	1.000	-	-		otm3208
orthoMCL	1	0.900	-	-		OOG6_103242
Panther	1	1.100	-	-	LDO	PTHR10540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3506
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840