DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and stambpa

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_956792.1	Gene:	stambpa / 797422	ZFINID:	ZDB-GENE-040426-1551	Length:	418	Species:	Danio rerio

Alignment Length:	198	Identity:	44/198 - (22%)
Similarity:	64/198 - (32%)	Gaps:	61/198 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ERRNADSHRVIGTLLGSVDKGVVEVTN------C----FCVPHKEHDDQVEAELSYALDMYDLNR 77
            |...|.:....|.|.|.:.|....||:      |    :|      |.:.|.||....|..||
Zfish   266 ETNTARAVETCGILCGKLMKNAFTVTHVIVPKQCGGPDYC------DTENEEELFLIQDQNDL-- 322

  Fly    78 KVNSNESVVGWWATGNDVTNH-SSV-IHEYYARECNNPVHLTVDTSLQGGRMGLRAYVCIQLGVP 140
                  ..:||..|....|.. ||| :|.:.:.:...|..:.:..|.:....|.
Zfish   323 ------ITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFNETGY----------- 370

  Fly   141 GGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLA---QISEASTKLQSL 202
                        ..||.|..:..|   ..|..|..|  .||. ||:...:   .|::.|.   ::
Zfish   371 ------------FRLTDYGMDDVG---TCKQRGFHP--HPKD-PPLFAASHHVSITDGSV---TM 414

  Fly   203 LDL 205
            |||
Zfish   415 LDL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	44/198 (22%)
stambpa	NP_956792.1	USP8_dimer	13..114	CDD:286108
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	199..218
		MPN_AMSH_like	248..418	CDD:163697	44/198 (22%)
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	329..342		4/12 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900