DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and Mpnd

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_038940132.1	Gene:	Mpnd / 681944	RGDID:	1589335	Length:	488	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	50/243 - (20%)
Similarity:	81/243 - (33%)	Gaps:	79/243 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VVLFQVVDAFERRNA----------DSH------RVIGTLLG--SVDKGVVEVTNCFCVPHKEHD 59
            |..|..::.|:..|.          |.|      .|:|.|.|  .::..::.|...|....:..|
  Rat   244 VTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGD 308

  Fly    60 DQ----VEAELSYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNN-PVHLTVD 119
            ..    ||.|:...|.:..|        |:|||:        ||.. |...|....: ...:...
  Rat   309 PDTAATVEEEIHQVLFLRGL--------SLVGWY--------HSHP-HSPAAPSLQDIDAQMEYQ 356

  Fly   120 TSLQGGRMGLRAYVCIQL-------GVPGGKSG-CMFTPIPVELTSYEPETFGLKLLQKTVGVSP 176
            ..|||...|.:.  |:.|       |.||.:|. |.|..:|.. ....|..:|
  Rat   357 LRLQGSNNGFQP--CLALLCSPYYSGNPGPESKICPFWVMPPP-EQQRPSDYG------------ 406

  Fly   177 AHRPKTVPPMLDLAQISEA---STKLQSLLDLILKYVDDVIAHKVTPD 221
                  :|..:::|.:.::   :..||.::.|:..|       |..||
  Rat   407 ------IPMDVEMAYVQDSFLTNDVLQEMMMLVEFY-------KGAPD 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	50/243 (21%)
Mpnd	XP_038940132.1	RAMA	57..157	CDD:408526
Mpnd	XP_038940132.1	MPN_2A_DUB	252..437	CDD:163698	45/229 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900