DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF3f1 and Eif3f

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_079620.2	Gene:	Eif3f / 66085	MGIID:	1913335	Length:	361	Species:	Mus musculus

Alignment Length:	277	Identity:	132/277 - (47%)
Similarity:	189/277 - (68%)	Gaps:	18/277 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VRVHPVVLFQVVDAFERRNADSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAELSYALDM 72
            ||:|||:|..:||::||||..:.||||||||:|||..|||||||.|||.|.:|:|..::.:|.:|
Mouse    96 VRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNM 160

  Fly    73 YDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLRAYVCIQL 137
            |:|::||:.||.::||:|||:|:|.||.:|||||:||..||:||||||.||.|||.::|||...:
Mouse   161 YELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTGLQHGRMSIKAYVSTLM 225

  Fly   138 GVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKT-------VGVSPAHRPKTVPPMLDLAQISEA 195
            ||||...|.||||:.|:...|:.|..|:.|:.||       :|:|.           ||.|:..|
Mouse   226 GVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSS-----------DLQQVGGA 279

  Fly   196 STKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRNLLLVITL 260
            |.::|..|..:|:|.:||::.||:.||.|||.|:.|::.||.:..:.|..|.|:|:.:||:|..|
Mouse   280 SARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYL 344

  Fly   261 SQLIKTQLQLNEKLTFL 277
            :.|.::|:.|||||..|
Mouse   345 ANLTQSQIALNEKLVNL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	129/272 (47%)
Eif3f	NP_079620.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91
Eif3f	NP_079620.2	MPN_eIF3f	96..358	CDD:163695	129/272 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837264
Domainoid	1	1.000	139	1.000	Domainoid score	I4801
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2783
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2987
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54712
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004972
OrthoInspector	1	1.000	-	-		oto92347
orthoMCL	1	0.900	-	-		OOG6_103242
Panther	1	1.100	-	-	LDO	PTHR10540
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R381
SonicParanoid	1	1.000	-	-		X3506
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790