DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and stambpl1

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_009304952.1	Gene:	stambpl1 / 570542	ZFINID:	ZDB-GENE-100215-4	Length:	466	Species:	Danio rerio

Alignment Length:	195	Identity:	44/195 - (22%)
Similarity:	64/195 - (32%)	Gaps:	55/195 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ADSH-----RVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAELSYALDMYDLNRKVNSNESVV 86
            |||:     ...|.|.|.:......:|:..........|..:.|....|..|    :.:.|...:
Zfish   267 ADSNTARGIETCGVLCGKLTHNEFVLTHVIVPKQSAGPDYCDMENVEELFSY----QDHHNLLTL 327

  Fly    87 GW---------WATGNDVTNHSS---VIHEYYARECNNPVHLTVDTSLQGGRMGLRAYVCIQLGV 139
            ||         :.:..|:..|||   ::.|..|..| .|.|          .....|:.|.
Zfish   328 GWIHTHPTQTAFLSSVDLHTHSSYQLMLPEAIAIVC-APKH----------NESFPAHQCW---- 377

  Fly   140 PGGKSGCM----FTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQISEASTKLQ 200
             .|:||.|    |:| |:|..|      .:..||...|    .|.|...|.   .|::|...|.|
Zfish   378 -NGRSGRMQIERFSP-PLERPS------SVHYLQAHCG----ERLKNDSPG---PQVTEEDGKYQ 427

Fly 201 200
Zfish 428 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	44/195 (23%)
stambpl1	XP_009304952.1	USP8_dimer	28..130	CDD:286108
stambpl1	XP_009304952.1	MPN_AMSH_like	250..>369	CDD:163697	23/116 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900