DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and Mysm1

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_017175747.1	Gene:	Mysm1 / 320713	MGIID:	2444584	Length:	824	Species:	Mus musculus

Alignment Length:	232	Identity:	47/232 - (20%)
Similarity:	79/232 - (34%)	Gaps:	47/232 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FQVVDAFER---RNADSH----RVIGTLLGS-------VDKGVVEVTNCFCVP--------HKEH 58
            |||..|.|.   .|..:|    .|||.|.|.       ::..:::|  |...|        ..|.
Mouse   566 FQVKVAAEALLIMNLHAHVSMAEVIGLLGGRYSEADKVLENNLLQV--CAAEPCNSLSTGLQCEM 628

  Fly    59 D--DQVEAELSYALDMYDLNRKVNSNESVVGWWATG---------NDVTNHSSVIHEYYARECNN 112
            |  .|.:|..:.||..|          ||:||:.:.         .|:...:. ...|::|....
Mouse   629 DPVSQTQASETLALRGY----------SVIGWYHSHPAFDPNPSLRDIDTQAK-YQSYFSRGGAK 682

  Fly   113 PVHLTVDTSLQGGRMGLRAYVCIQLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPA 177
            .:.:.|....:...:......|:.:.......|....|...|:.....|.....:.:||..:...
Mouse   683 FIGMIVSPYNRSNPLPYSQITCLVISEEVSPDGTYRLPYKFEVQQMLEEPQWELVFEKTRWIIEK 747

  Fly   178 HR-PKTVPPMLDLAQISEASTKLQSLLDLILKYVDDV 213
            :| ..:..||..:.:.....|.||.||:.:.|.:..|
Mouse   748 YRLSNSSVPMDRIFRRDSDLTCLQKLLECLRKTLSKV 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	47/232 (20%)
Mysm1	XP_017175747.1	Myb_DNA-binding	116..160	CDD:365977
		SWIRM	373..452	CDD:367940
		MPN_2A_DUB	562..749	CDD:163698	37/195 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900