DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f1 and Mysm1

DIOPT Version :9

Sequence 1:	NP_649489.1	Gene:	eIF3f1 / 40587	FlyBaseID:	FBgn0037270	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_008762133.1	Gene:	Mysm1 / 298247	RGDID:	1311787	Length:	811	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	51/268 - (19%)
Similarity:	94/268 - (35%)	Gaps:	80/268 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 KEHDDQVEAELSYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYA----RECNNPVHL 116
            :|.|..||.:::.|..                   .||| .|.:||..::|.    |..|..:..
  Rat     4 EEADVDVEGDVAAAAQ-------------------PGND-GNTASVFQDHYLDSTWRRENGCLPW 48

  Fly   117 TVDTSLQGGRMGL-------RAYVCIQLGVPG-----------------GKSGCMFTPIPVELTS 157
            |:|:::......:       ..|......:||                 .|:|.:....|.:.:|
  Rat    49 TLDSTISDENRAVIEKMLLEEEYYLSNKSLPGKFWVNQKENDKKCTNSLQKTGKIMVRSPAKPSS 113

  Fly   158 Y-------EPETF--GL-KLLQKTVGVSPAHRPKTVPPMLDLAQ----------ISEASTKLQSL 202
            |       |.:.|  || |..::...::...:.:||..:...|:          ..:.:..|:|.
  Rat   114 YSVKWTIEEKKLFEQGLAKFGRRWTKIAALVKSRTVLQVKSYARQYFRNKVKWGAEKETPTLKSN 178

  Fly   203 LDLILKYVDDVIAHKVTPD---NAVGRQLL------DLIHSVPHMTHEQFTQMFNANVRNLLLVI 258
            .||.:|..|:.....|..|   |||..:.|      |:...:..:|.:...:.:..   :|.|.:
  Rat   179 SDLQVKNKDERTKVWVASDPNLNAVKIEKLSDDEDVDITDELDELTSQTSQKNYGG---HLTLDV 240

  Fly   259 TLSQLIKT 266
            ..|::.||
  Rat   241 PSSKMYKT 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	51/268 (19%)
Mysm1	XP_008762133.1	Myb_DNA-binding	116..160	CDD:395191	8/43 (19%)
		SWIRM	365..444	CDD:398234
		MPN_2A_DUB	554..736	CDD:163698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900