Protein Alignment eIF3f1 and COPS6

DIOPT Version :9

• Sequence 1: NP_649489.1
• Gene: eIF3f1 / 40587
• FlyBaseID: FBgn0037270
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_006824.2
• Gene: COPS6 / 10980
• HGNCID: 21749
• Length: 327
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 58/271 - (21%)
• Similarity: 121/271 - (44%)
• Gaps: 7/271 - (2%)

  Fly     5 NLTVRVHPVVLFQVVDAFERRNADSHR---VIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAEL 66
            :::|.:||:|:..:.|.:.|..:...|   |||.|:|..:...:||.|.|.:.....::::..:.
Human    38 SVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDK 102

  Fly    67 SYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLRA 131
            .|.....:..::|......:||:.||.........:|:.......:|:.|.::...:...:.:..
Human   103 EYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSV 167

  Fly   132 YVCIQLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQISEAS 196
            :..: :.:..|::..:|..:...|.:.|.|..|:..:.:......... .||...| :||.| |.
Human   168 FESV-IDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGEN-STVAEHL-IAQHS-AI 228

  Fly   197 TKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRNLLLVITLS 261
            ..|.|.:.|||:||....|.:|..::.:.|:...|.|.:|.::.::|...|.....::.|:..|.
Human   229 KMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLG 293

  Fly   262 QLIKTQLQLNE 272
            .:.||...:|:
Human   294 TITKTCNTMNQ 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f1	NP_649489.1	MPN_eIF3f	8..274	CDD:163695	58/268 (22%)
COPS6	NP_006824.2	MPN_CSN6	39..321	CDD:163694	58/270 (21%)
		Interaction with Vpr	211..327		27/97 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810