Sequence 1: | NP_001246912.1 | Gene: | smash / 40583 | FlyBaseID: | FBgn0263346 | Length: | 1541 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_055055.1 | Gene: | LIMD1 / 8994 | HGNCID: | 6612 | Length: | 676 | Species: | Homo sapiens |
Alignment Length: | 600 | Identity: | 112/600 - (18%) |
---|---|---|---|
Similarity: | 186/600 - (31%) | Gaps: | 249/600 - (41%) |
- Green bases have known domain annotations that are detailed below.
Fly 1113 LKRQRENLVLRENIARRELQHGAKMLMSNNRRSLQDLHHGLG-------IGNGML--SAFQPPQH 1168
Fly 1169 HQVQMP----------PPHPQQIYANVPQQQQQMVLHA--YHQMDTDYRKSM--SDLNEF----- 1214
Fly 1215 ---SNCLIL---------------------------------------PPTPP---TKPLRAMQL 1234
Fly 1235 NAN-----------------GHGLEPD---YAVSTRQRQPPAPYGGSLVKIAGA--PMPPRLPGQ 1277
Fly 1278 GYPIQAPTAPAYHHQSAQNLSN----------MSRNTLLALSATPKPKYADGWVQVQQRKSY--D 1330
Fly 1331 SQQTSDAAWLAAQQQKRKSMPDYG--------GALYNNNHWLLQEAEQRRIEQLNRRSIP----A 1383
Fly 1384 SKSMGKPLPDS--------------------------IIQTLTERVQ------------------ 1404
Fly 1405 SKGI-GDRKRFDSNGNY------------SQVNGNNIYQQQQQQKNVTNGSSINGNSSQGQEKVL 1456
Fly 1457 SVSGKKKCS----HCG-DELGKLCYYVGCRGAAMIIESLLLFYHINCFKCCVCHVQLGDGLNGTD 1516
Fly 1517 VRV-RNHKLHCQNCY 1530 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
smash | NP_001246912.1 | DUF4757 | 14..152 | CDD:292571 | |
LIM | <1494..1530 | CDD:278823 | 11/36 (31%) | ||
LIMD1 | NP_055055.1 | Mediates nuclear export | 54..134 | 19/95 (20%) | |
Atrophin-1 | <69..443 | CDD:331285 | 75/409 (18%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 104..163 | 14/64 (22%) | |||
Interaction with EGLN1/PHD2 | 186..260 | 9/73 (12%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 189..389 | 43/216 (20%) | |||
Interaction with RB1. /evidence=ECO:0000269|PubMed:15542589 | 404..442 | 6/37 (16%) | |||
Necessary for nuclear localization | 472..676 | 29/148 (20%) | |||
LIM1_Ajuba_like | 472..525 | CDD:188738 | 12/79 (15%) | ||
LIM2_Ajuba_like | 537..589 | CDD:188741 | 16/55 (29%) | ||
LIM3_Ajuba_like | 597..658 | CDD:188822 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1704 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |