Protein Alignment smash and prickle2a

DIOPT Version :9

• Sequence 1: NP_001246912.1
• Gene: smash / 40583
• FlyBaseID: FBgn0263346
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_001071251.2
• Gene: prickle2a / 777736
• ZFINID: ZDB-GENE-061110-112
• Length: 869
• Species: Danio rerio
• Alignment Length: 702
• Identity: 125/702 - (17%)
• Similarity: 188/702 - (26%)
• Gaps: 298/702 - (42%)

  Fly   749 QTSNSNENNQSTNQTSNSRNQKESSTAATSAANPVPPTTPGEQAEPYYQVPKATEPYYDAPKHLR 813
            |::.|.:::.|.:...:....|..:...||:.    |||....|||.
Zfish   323 QSARSRQSHHSASVGKDGSKGKGEAVRQTSSG----PTTLSGDAEPL------------------ 365

  Fly   814 PVPVYENVEIFYSGLEISQGSVGAPVGLMEPPKEKPPPPPTESPIPLDEGHDDELDGLGNSLGHN 878
                         .:::...||.:|.     |...|...||.:|        ........||...
Zfish   366 -------------AVQMDLLSVASPA-----PSRTPHRTPTRTP--------SRTSSRSPSLNRE 404

  Fly   879 TDTWSSDNTYETISNGTRRHLQGQPEPAQ------------PSP--PIKRMNSTKRIKKELRNKR 929
            ...|.  |..|..|..::|.....|.|.|            |||  |.|.::|.:...||.....
Zfish   405 QTVWV--NRDEPYSYESQRDSSTSPNPHQLRSQCSIRTAYPPSPNQPPKIVSSQEAWSKEPPGGN 467

  Fly   930 SSFLGIENDGDLDDMETYLELTVAPPPDMAQLLQEERRLEKQLYIKAGLCDSSDTGESRDSGVSE 994
            |.                      .||.||.|                          |....:|
Zfish   468 SK----------------------KPPVMAAL--------------------------RGHSFNE 484

  Fly   995 NHSRQSSEHYTNSSEENDTQSEATPPPLPPPPSTAQV--GEVIYQNESLLAAQ------------ 1045
            |......|                 |...||....|:  .||..:|...|..:
Zfish   485 NWMHHGQE-----------------PEFHPPKLKTQMSFNEVSSRNSGFLDKRSISVQGFPREMR 532

  Fly  1046 -----------------TPLLQTVKGNSAESWTESATAAAAATQSLSEATATANAKMQSIEDKIR 1093
                             |||.||.:|::               .||:.:..|.|    |::...|
Zfish   533 PLLLRGRHQFRPNFGELTPLEQTPRGSA---------------DSLALSYTTGN----SLDGTSR 578

  Fly  1094 EQGEMLRVERELLHFSQEELKRQRENLVLRENIARR--------ELQHGAKMLMSNNRRSLQDL- 1149
            .|....|       ||..:|.:..     ..|::.:        .:|..:...:|:..|.|.|:
Zfish   579 RQEHFSR-------FSMPDLSKDS-----GVNVSEKGTVGTLNSSVQFRSTESLSSVPRPLADIG 631

  Fly  1150 ---------------HHGLGIGN------GMLSAFQPPQHHQVQMPPPHPQQIYA-NVPQQQQQM 1192
                           ..||...:      |:..:....|....|...|.|::..| |.|:||:|.
Zfish   632 MPVRLRYPPPLYWDSPRGLSFEDPVKGRIGLAGSMSCMQDGNAQAMTPRPRRAQAQNSPRQQRQR 696

  Fly  1193 VLH---AYHQMDTDY--RKSMSDLNEFSNCLILPPTP---PTKPLR----------AMQLNANGH 1239
            ..|   .:......|  |:|.||     |.|.|....   |..|:.          :.:|:.|..
Zfish   697 QRHHRKNHKSQKYQYRSRRSRSD-----NALHLATEDQSFPGDPIHRFHNDFERPSSSRLSHNLF 756

  Fly  1240 GLEPDYAVSTRQ---------------RQPPAPYGGSLVKIAGAPMPPR---------------- 1273
            |....|    ||               :.|..|..|..:...|..:...
Zfish   757 GANYGY----RQQFFRPCPRTTSDLTLQDPGGPQIGQYMGRYGEAVEDEDQFCSTCSSSSEASDD 817

  Fly  1274 ---LPGQGY--PIQ-------------APTAPAYHHQSAQNLSNMSRNTLLA 1307
               |||:|.  |:|             :||....|.|........|:|.:::
Zfish   818 DAYLPGEGIPRPVQLRYFDNEELRHRYSPTLVGGHTQLHTRKRRKSKNCIIS 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
		LIM	<1494..1530	CDD:278823
prickle2a	NP_001071251.2	PET_Prickle	22..118	CDD:193602
		LIM1_Prickle	126..184	CDD:188799
		LIM2_Prickle	189..244	CDD:188802
		LIM3_Prickle	249..307	CDD:188804

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900