DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smash and fblim1

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_001070771.1	Gene:	fblim1 / 768160	ZFINID:	ZDB-GENE-061013-662	Length:	292	Species:	Danio rerio

Alignment Length:	327	Identity:	63/327 - (19%)
Similarity:	108/327 - (33%)	Gaps:	109/327 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1261 SLVKIAGAPMPPRLPGQGYPIQ----APTAPAYHH------QSAQNLSNMSRNTLLALSATPKPK 1315
            :|...:.|.:.|...||..|.:    |||.|...|      .:.::|.:..|:    ||..|.
Zfish    17 TLASPSRATVTPTAHGQHSPARAQNTAPTGPCRTHVVSGVPPAPRDLCDPKRD----LSGGPA-- 75

  Fly  1316 YADGWV-------QVQQRKSYDSQ-QTSDAAWLAAQQ--------------------QKRKSMPD 1352
             .||.|       ..|:::..|:. ..||......:|                    |.|:....
Zfish    76 -EDGAVLRSAPSAGGQEKQQSDTHTHCSDVCGFCRKQVSPCESAIVALNRCYHSGCFQCRQCCAP 139

  Fly  1353 YGGALYNNNHWL-LQEAEQRRIEQLNRRSIPASKSMGKPLPDSIIQTLTERVQ----------SK 1406
            ..|..|.:...| |.||       .::.|:....:.|..:.|.:|:.| ||..          .:
Zfish   140 LAGRQYYSRSGLPLCEA-------CHQASLEPCWACGDVIKDHVIRAL-ERAYHPPCFVCTTCRQ 196

  Fly  1407 GIGDRKRFDSNGNYSQVNGNNIYQQQQQQKNVTNGSSINGNSSQGQEKVLSVSGKKKCSHCG--- 1468
            .||:::       ::|.....:|..|...:...                      .:|..||
Zfish   197 PIGEQR-------FAQGEVGEVYCLQDYYRKYA----------------------PQCGVCGLMI 232

  Fly  1469 ---DELGKLCYYVGCRGAAMIIESLLLFYHINCFKCCVCHVQLGDGLNGTDVRVRNHKLHCQNCY 1530
               |: |...:.|.|.|.:         ||.:|::|.||.|.|....:.......:.::.|:.|:
Zfish   233 IPRDD-GTDSFTVECLGRS---------YHEDCYRCQVCAVLLSPEPDERGCHPLDGQMLCRTCH 287

  Fly  1531 SS 1532
            |:
Zfish   288 SA 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	9/35 (26%)
fblim1	NP_001070771.1	LIM	<100..158	CDD:295319	11/64 (17%)
		LIM	165..217	CDD:295319	11/59 (19%)
		LIM	225..287	CDD:295319	17/71 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900