DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smash and lims2

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	XP_021334342.1	Gene:	lims2 / 553696	ZFINID:	ZDB-GENE-050522-56	Length:	378	Species:	Danio rerio

Alignment Length:	214	Identity:	43/214 - (20%)
Similarity:	74/214 - (34%)	Gaps:	63/214 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1365 LQEAEQRRIEQLNRRSIPASKSMGKP----------------------LPDSIIQTLTERVQSKG 1407
            :.|||....| |:...:..:::.|:|                      :.:::...:.||.:|..
Zfish     1 MMEAEAEAPE-LDVDGLQQNQTAGEPEVPKRSDVKVYKEFCDFYVRYNMTNALANAVCERCKSSF 64

  Fly  1408 IGDRKRFDSNGNYSQVNGNNIYQQQ-----QQQKNVTNGSSINGNSSQGQEKVLSVSGKKKCSHC 1467
            ....|..:|||        .:|.:|     |..:.:..|            ......|:|.|.|.
Zfish    65 SPTEKMVNSNG--------ELYHEQCFTCAQCFQQLIQG------------LFYEFEGRKYCEHD 109

  Fly  1468 GDEL-GKLCYYVGCRGAAMIIESLLLFYHINCFKCCVCHVQLGD-GLNGTDVRVRNHKLHCQNCY 1530
            ...| ...|:..|......:|:::...:|.:||.|.||...|.| |.    |:.....| |::|:
Zfish   110 FQMLFAPCCHQCGEFVVGRVIKAMNSSWHPDCFCCEVCEAVLADVGF----VKSGGRPL-CRSCH 169

  Fly  1531 SSDDGI--------KFSCV 1541
            |....:        |..||
Zfish   170 SRQKALSLGKHVCQKCLCV 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	12/36 (33%)
lims2	XP_021334342.1	LIM1_PINCH	57..115	CDD:188717	16/77 (21%)
		LIM2_PINCH	118..169	CDD:188718	15/55 (27%)
		LIM3_PINCH	182..231	CDD:188719	3/7 (43%)
		LIM4_PINCH	237..290	CDD:188720
		LIM5_PINCH	298..351	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900