DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smash and lmcd1

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_957364.2	Gene:	lmcd1 / 394045	ZFINID:	ZDB-GENE-040426-1067	Length:	342	Species:	Danio rerio

Alignment Length:	319	Identity:	61/319 - (19%)
Similarity:	100/319 - (31%)	Gaps:	118/319 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly  1290 HHQSAQNLSNMSRNTLLALS----ATPKPKYADGWVQVQQRK-------------------SYDS 1331
            |...:.|..::....|||.|    .|.|.|..|| .:|.:|.                   :||.
Zfish    43 HAFISNNEDDLKVGRLLADSRYTHLTAKVKGGDG-TRVYKRNRMIVTNPVVSRKDPTFNTVTYDW 106

  Fly  1332 QQTS-----DAAWLAAQQQKRKSMPDYGGALYNNNHWLLQEAEQRRIEQLNRRSIPA---SKSMG 1388
            ..|.     ...:::...::|:.:....|:||             |.:||.|: :||   ..:..
Zfish   107 APTGLTQKLAMLYMSLLPEERRPVAGTEGSLY-------------RHKQLTRQ-LPAYDHDPAYC 157

  Fly  1389 KPLPDSIIQTLTERV-----QSKGIGDRKRFDSNGNYSQVNGNNIYQQQQQQKNVTN---GSSIN 1445
            ..|.::.::.:.:.|     :|.|:|:   ....|..|....|....|:|....:|.   ..:|.
Zfish   158 HSLSEAELKVMAQFVKSYKEESLGVGE---VALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIE 219

  Fly  1446 GNSSQGQEKVLSVSGKKK------------------------CSHCGDELGKLCYY--------- 1477
            ...|...|...|..|:..                        |..||:.|..|.|:
Zfish   220 SPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCG 284

  Fly  1478 -----------VGCRGAAMIIESLLL------FYHINCFKCCVCHVQLGDGLNGTDVRV 1519
                       :||  ..:|...:||      .:|...|.|.:|         |.|:||
Zfish   285 RHYCQSIRPRCLGC--DELIFSDMLLQEASGHVWHKEHFCCWLC---------GQDIRV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	8/26 (31%)
lmcd1	NP_957364.2	PET_testin	102..189	CDD:193604	18/103 (17%)
		LIM1_Testin_like	230..287	CDD:188726	8/56 (14%)
		LIM	293..>326	CDD:295319	8/34 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900