Protein Alignment smash and Tes

DIOPT Version :10

• Sequence 1: NP_001246912.1
• Gene: smash / 40583
• FlyBaseID: FBgn0263346
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_611215.1
• Gene: Tes / 36965
• FlyBaseID: FBgn0034223
• Length: 816
• Species: Drosophila melanogaster
• Alignment Length: 689
• Identity: 139/689 - (20%)
• Similarity: 236/689 - (34%)
• Gaps: 209/689 - (30%)

  Fly   948 LELTVAPP---PDM----------AQL--------LQEERRLEKQL---YIKAGLCDSSDTGESR 988
            ::|...||   ||:          ||:        |:.:.:||.|:   .:.|.|||
  Fly   110 VQLEWVPPNAAPDVVTDYMEKLGTAQIPVAGSDAALKRKMQLELQVPPHDLDAALCD-------- 166

  Fly   989 DSGVSENHSRQSSEHYTNSSEE--------------NDTQSEATPPPLPPPPSTAQVGEVIYQNE 1039
              |::|..:.|..::.....|:              |..|.|...|.|.|    .|..:..:|:.
  Fly   167 --GLTETEAIQLQQYVQKLREQCVGQGVVVRLGDRLNHAQVEHVAPALMP----TQEAQQTWQSL 225

  Fly  1040 SLLAAQTPLLQTVKGNSAESWTESATAAA------AATQSLSEATATANAKMQSIEDKIREQGEM 1098
            .|:......|..:..|...:...::.|:|      |.::.|.|:||           :..|.|.:
  Fly   226 GLMPVADDTLNELLANPKVAQALASPASAHPKLLVAFSEPLCESTA-----------QFEENGAL 279

  Fly  1099 LRVERE-LLHFSQEELKRQRENLVLRENIARRELQHGAKMLMSNNRRSLQDLHHGLG-------- 1154
            ....|| ||..|:..|.....:.::.:.:.  .:....|:.:|.:.:        ||
  Fly   280 RAQTREKLLGISKPALLSLVTHGIVYDKVL--GILQEKKLNISRDPK--------LGPIAEFRKE 334

  Fly  1155 -IGNGMLSAF------QPPQHHQVQMPPPHPQQIYANVP---QQQQQMVLHAYHQMDTDYRK--- 1206
             :.|....|.      |||. ..::.||..|    .|.|   :...|:.:.|..:.||..|:
  Fly   335 YVNNPQFRAEINTICPQPPM-TPIKSPPGTP----FNSPLPLKNPVQIRMGAQMRQDTPMRRVKF 394

  Fly  1207 -SMSDLNEFSNCLILPPTPPTK-PLRAMQLNANGHGLEPDYAVSTRQRQPPAPYGGSLVKIAGAP 1269
             .:|.:  ..:|.:...|...: |:.|..|.|     ||........|...||   |.|.|:..|
  Fly   395 GGVSTI--VYDCGLPANTDYDRDPVFAQILQA-----EPLKHAFQEARAGRAP---SSVVISNIP 449

  Fly  1270 MP----PRLPGQGYPIQAPTAPAYHHQSAQNLSNMSRNTLLALSATPKPKYADGWVQVQQRKSYD 1330
            .|    ..|.|..        ||...|    |.::..:..:..||.....|.|...    |..:|
  Fly   450 APVASLAELRGLN--------PATRAQ----LQSVGLDKNMLQSAVSNAPYYDRLF----RSLHD 498

  Fly  1331 SQQTSDAAWLAAQQQKRKSMPDYGGALYNNNHWLLQEAEQRRIEQLNR---------RSIPASK- 1385
            ...:.|...|.   |..|.:.|          |||.  :.:.::::::         :.|...|
  Fly   499 KGISHDQCHLL---QPMKQVHD----------WLLD--DDQLLDEIDKVFADMANGCKDISYPKP 548

  Fly  1386 SMGKPLPDSIIQTLTERVQSK----GIGDRKRFDSNGNYSQVNG---NNIY-------QQQQQQK 1436
            |:|: ||.|  |:......||    |.|........|.::.:.|   .|:|       :|.||.:
  Fly   549 SLGE-LPTS--QSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLR 610

  Fly  1437 NVTNGSSINGNSSQGQEKVLSVSGKKKCSHCGD--ELGKLCYYVGCRGAAMIIESLLLFYHINCF 1499
                   ::|:.:.|:....::    .|:.|..  .:|::.......|..       :.:|..||
  Fly   611 -------LHGDEASGKNSTRTI----LCADCNQPIAMGEVAVKADRAGKE-------IAWHPGCF 657

  Fly  1500 KCCVCHVQLGDGLN---------GTDVRVRNHKLHCQNC 1529
            ||..|...|.|.:.         |.|:.:|.....|:.|
  Fly   658 KCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRAC 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	<47..153	CDD:464950
		PAT1	<1159..>1335	CDD:401645	43/193 (22%)
		LIM	<1494..1530	CDD:395333	13/45 (29%)
Tes	NP_611215.1	PET_testin	110..197	CDD:193604	19/96 (20%)
		LIM1_Testin_like	627..684	CDD:188726	13/63 (21%)
		LIM2_Testin_like	691..748	CDD:188727	2/6 (33%)
		LIM	755..810	CDD:413332