DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smash and Tesl

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_001107222.1	Gene:	Tesl / 316142	RGDID:	1305365	Length:	406	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	62/337 - (18%)
Similarity:	101/337 - (29%)	Gaps:	126/337 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly  1273 RLPGQGYP-----IQAPTAP-----------AYHHQSAQNLSNMSRNTLLALSATPKPKYADGWV 1321
            :|..:|.|     :.|.|.|           :|..........::||.:    |..|...:..|.
  Rat    69 KLKSEGMPMFKHNVMAMTNPCTAEKKFFNTGSYEWAPPVQRQELARNYM----AKEKLSLSGSWA 129

  Fly  1322 QVQQRKSYDSQQTSDAAWLAAQQQKRKSMPDYGGALYNNNHWLLQEAEQRRIEQLNRRSIPASKS 1386
            ....:|....|       |.|..|......:            |...|.|.:||..::
  Rat   130 TQYLKKQLSKQ-------LPAHDQDPSKCHE------------LSPNEVREMEQFIKK------- 168

  Fly  1387 MGKPLPDSIIQTLTERVQSKGIGDRKRFDSNGNYSQVN--GNNIYQQQQQQKNVTNGSSINGNSS 1449
                          .:.::.|:|..|      :.|:||  |:.: |...:.:|.|:..|....|:
  Rat   169 --------------YKNEALGVGAMK------HLSEVNDQGDKV-QNPARVRNTTSALSSKEKST 212

  Fly  1450 QGQEKVLSV------------------SGKKK--------CSHCGDELGKLCY-------YVG-- 1479
            :.::...|.                  :|..|        ||.||:.|..:.|       |.|
  Rat   213 EPKKTQYSCYCCKQPIKEGDTAIYAERAGYNKLWHPSCFICSTCGELLVHMIYFWKNGKLYCGRH 277

  Fly  1480 --------CRGAAMIIESLLLF------YHINCFKCCVC--------HVQLGDGLNGTDVRVRNH 1522
                    |.|...:|.|....      :|:..|.|..|        :|.:.|........::||
  Rat   278 YCDSEKPRCAGCDELIFSKEYTQAENQNWHLKHFSCFDCDKILAGKIYVMVNDKPVCKPCYMKNH 342

  Fly  1523 KLHCQNCYSSDD 1534
            .:.||.|.|..|
  Rat   343 AVKCQECQSVID 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	10/43 (23%)
Tesl	NP_001107222.1	PET_testin	101..183	CDD:193604	19/131 (15%)
		LIM1_Testin	221..278	CDD:188797	10/56 (18%)
		LIM2_Testin	284..339	CDD:188800	10/54 (19%)
		LIM	346..404	CDD:295319	5/9 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900