Protein Alignment smash and PRICKLE4

DIOPT Version :9

• Sequence 1: NP_001246912.1
• Gene: smash / 40583
• FlyBaseID: FBgn0263346
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_037529.3
• Gene: PRICKLE4 / 29964
• HGNCID: 16805
• Length: 384
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 36/197 - (18%)
• Similarity: 71/197 - (36%)
• Gaps: 72/197 - (36%)

  Fly  1382 PASKSMGKPLPDSI-------IQTLTERVQSKGIGDRKRFDSNGNYSQVNGN------NIYQQQQ 1433
            ||..|:|....|:.       :|||.:::..:.|.:|        |....|.      .::..::
Human    46 PAVLSLGSLCLDTNQAPNWTGLQTLLQQLPPQDIDER--------YCLALGEEERAELQLFCARR 102

  Fly  1434 QQKNVTNG------SSINGNSSQ--------GQEKVLSV-SGKKKCSHCGDELGKLCYYVGCRGA 1483
            :|:.:..|      ..:.|::.:        |:..|.:. :|:::|.|      :.|:  .|:..
Human   103 KQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWH------QPCF--ACQAC 159

  Fly  1484 AMIIESLLLFYHINCFKCCVCHVQL-------------------GDGLNGTDVRVRNHKLH--CQ 1527
            ...:.:|:.|||.....|...|.:|                   .:|       .|.|:.|  ||
Human   160 GQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG-------QRWHENHFCCQ 217

  Fly  1528 NC 1529
            :|
Human   218 DC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
		LIM	<1494..1530	CDD:278823	12/57 (21%)
PRICKLE4	NP_037529.3	PET_OEBT	1..116	CDD:193603	14/77 (18%)
		LIM1_Testin_like	124..181	CDD:188726	12/64 (19%)
		LIM2_Testin_like	187..242	CDD:188727	7/40 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900