Protein Alignment smash and Prickle2

DIOPT Version :10

• Sequence 1: NP_001246912.1
• Gene: smash / 40583
• FlyBaseID: FBgn0263346
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_001391015.1
• Gene: Prickle2 / 243548
• MGIID: 1925144
• Length: 937
• Species: Mus musculus
• Alignment Length: 331
• Identity: 73/331 - (22%)
• Similarity: 126/331 - (38%)
• Gaps: 64/331 - (19%)

  Fly  1124 ENIARRELQHGAKMLMSNNR--RSLQDLHHGLGIGNGMLSAFQPPQHHQV-------QMPPPHPQ 1179
            :|...:|.:..||:..:..:  .::.:.|..|.:.:..|||...|...|:       |.|..:..
Mouse   419 QNARAKESRRSAKIGKNKGKTEEAMLNQHSQLQVSSNRLSADVDPLSVQMDLLSLSSQTPSLNRD 483

  Fly  1180 QIYANVPQQQQQMVLHAYHQMDTDYRKSMSDLNEFSNCLILPPTPPTKPLRAMQLNANGHGLEPD 1244
            .|:     :.::...|..::|:.:  :|.|.|...|.|.|.....|         ...|.|.:||
Mouse   484 PIW-----RSREEPFHYGNKMEQN--QSQSPLQLLSQCNIRTSYSP---------GGQGAGAQPD 532

  Fly  1245 Y---AVSTRQRQPPAP---YGGSLVKIAGAPMPPRLPGQGYPIQAPTAPAYHHQSAQNLSNMSRN 1303
            .   ..|..:|.....   :|||.::        ......||.:..:..:|...|:|:. |.:|.
Mouse   533 MWAKHFSNPKRSSSMALKGHGGSFIQ--------ECREDYYPGRLMSQESYSDMSSQSF-NETRG 588

  Fly  1304 TLLALSATPKPKY------ADGWVQVQQ---RKSYDS-QQTSDAAWLAAQQQKRKSMPDYGGALY 1358
            ::      |.|||      .:|.:..||   |:...| :.|.|..  ..:|..|.||....   .
Mouse   589 SI------PVPKYEEEEEEEEGGISTQQCRPRRPLSSLKYTEDMT--PTEQTPRGSMESLA---L 642

  Fly  1359 NNNHWLLQEAEQRRIEQLNRRSIP-ASKSMGKPLPDSI--IQTLTERVQSKGIGDRKRFDSNGNY 1420
            :|...|..|...:|.|.|:|.|:| .||..|..:.:.:  :.||...:|.:.....:...|...|
Mouse   643 SNATGLSAEGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFRSAESVRSLLSAQQY 707

  Fly  1421 SQVNGN 1426
            .::.||
Mouse   708 QEMEGN 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	<47..153	CDD:464950
		PAT1	<1159..>1335	CDD:401645	42/198 (21%)
		LIM	<1494..1530	CDD:395333
Prickle2	NP_001391015.1	PET_Prickle	118..214	CDD:193602
		LIM1_Prickle	222..280	CDD:188799
		LIM2_Prickle	285..340	CDD:188802
		LIM3_Prickle	345..403	CDD:188804