Protein Alignment smash and Zfp185

DIOPT Version :10

• Sequence 1: NP_001246912.1
• Gene: smash / 40583
• FlyBaseID: FBgn0263346
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_033575.3
• Gene: Zfp185 / 22673
• MGIID: 108095
• Length: 486
• Species: Mus musculus
• Alignment Length: 570
• Identity: 117/570 - (20%)
• Similarity: 183/570 - (32%)
• Gaps: 223/570 - (39%)

  Fly   178 NDLSDLGIGTSSASG-------------KSSLSGD------YDN------------------NSV 205
            :.|..:|.|.:..||             :::|.||      :|:                  :||
Mouse     4 SSLGSIGKGRTVPSGEEERNNILRQMKVRTTLKGDQSWITKHDDSEDHTIEPLSRHNRATSFSSV 68

  Fly   206 MSDHAAELDKAIGAASSVAAGVTAQNVDEQLNHINRNGSNGNHGNGAAVGQTGPSNSSKSAGRQY 270
            ..:..|....|...|..:..||..:.:|.. :|.....|..|....:|.||.|.:||
Mouse    69 RDESNARSPNARAPAGYIIRGVFTRTIDSS-SHSQHRPSKTNGAPRSASGQLGAANS-------- 124

  Fly   271 ISSPGYDTSSSNAQASSPDLCEYTYEGAIQDYKQRVQRASSNGNGNANGKLIGEHIAYPTRRGSK 335
                |:...||.            |:...:|||:..                    .|..||.|
Mouse   125 ----GHPLQSSG------------YKMTTEDYKKLA--------------------PYNIRRSS- 152

  Fly   336 IEDRLSGFEVTSPSDTQEGVEKQKVDVP-KVDISKRKEIFEQAKAEVSNGGAPAAPKLVFRDGLT 399
                :||.|              :.:|| ..|..||:   .||...|....||.....|    |:
Mouse   153 ----ISGTE--------------EEEVPFTPDEQKRR---SQAALGVLRKTAPREHSYV----LS 192

  Fly   400 NGNSATTAPKSEVRRLSGDISSIRDRMQSLEQQRKAFSSSKSVDVPVPPLKQRLNSLQQSVAKEE 464
            .....|::|..|              :||                  |.|.:|::.:.:.|..|:
Mouse   193 AAKKTTSSPTQE--------------LQS------------------PFLAKRVDVVDEDVLPEK 225

  Fly   465 QKKPPLVALIDARQLEIMRGEEERMRQQQ----QKEKH--SPSQTTL-----CAPKPAPPALIIE 518
            .::||.:|..|..:   .....|::..:|    ..|.|  :|....|     |....|.|.:|.|
Mouse   226 NQEPPALARPDPGR---SSSTTEKIAHRQITPPTAELHLVAPDLEALSTPDSCEENNAAPKIIKE 287

  Fly   519 EPPVADTNDDSGIQEDTADELQQQQQLNAAIAALALEERQLEEAANAVNQIEAEFDELTDLHPSP 583
            .|        ..:|:..:|.....|||    |.|::.|.| ...:.|..||:||  :.|::..|
Mouse   288 IP--------GTLQDGQSDPTVASQQL----ADLSILEPQ-GSPSGAEQQIKAE--DCTNMLMS- 336

  Fly   584 LPPSPALPAV-------QQSLQQPTV-AQVPAQAV--------------NQAAAPPLR---DMEF 623
              ||..:..|       |..|..|.| ::|.:.:.              ..::..|:.   |...
Mouse   337 --PSSCMVTVTISDTSEQSQLCVPGVSSKVDSSSTIKGILFVKEYMNTSEVSSGKPVSSHCDSPS 399

  Fly   624 SINEALELALQAIDREATTKPMDKAQHPQKREQKEELGGKPEEK--EPIC 671
            ||.::|:||             .||.|.          |.|.|:  |.:|
Mouse   400 SIEDSLDLA-------------KKAPHE----------GTPSERPTEGVC 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	<47..153	CDD:464950
		PAT1	<1159..>1335	CDD:401645
		LIM	<1494..1530	CDD:395333
Zfp185	NP_033575.3	LIM	425..481	CDD:214528	1/2 (50%)