DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smash and Fhl4

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_034344.2	Gene:	Fhl4 / 14202	MGIID:	1338765	Length:	279	Species:	Mus musculus

Alignment Length:	150	Identity:	31/150 - (20%)
Similarity:	45/150 - (30%)	Gaps:	47/150 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1423 VNGNNIYQQQQQQKNVTNGSSINGNSSQGQEKVLSVSGKK-------------KCSHCGDELGK- 1473
            :.|....|:......||...|...|..|...|.:....|:             |||.|...|..
Mouse    13 LQGKKYVQKDGANYCVTCFDSHCANICQECHKPIGADSKEVCYKEQFWHNTCFKCSKCSQLLATE 77

  Fly  1474 ---------LC-------YYVGCRGAAMIIE----------SLLLFYHINCFKCCVCHVQLGDGL 1512
                     ||       .:..|:|....||          |:   :|.|||.|..|.    |.:
Mouse    78 TFVAWDKNILCNKCATRVTFPKCKGCLKDIEEGDHNVEYKGSI---WHKNCFVCTNCK----DII 135

  Fly  1513 NGTDVRVRNHKLHCQNCYSS 1532
            ...:...::...:|..||.:
Mouse   136 GTKNFFPKDEGFYCVTCYDA 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	8/35 (23%)
Fhl4	NP_034344.2	LIM	<4..32	CDD:295319	4/18 (22%)
		LIM	39..92	CDD:295319	10/52 (19%)
		LIM2_FHL1	100..157	CDD:188808	15/62 (24%)
		LIM3_FHL1	161..213	CDD:188813
		LIM4_FHL1	216..279	CDD:188734
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900