DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment smash and Fhl1

DIOPT Version :9

Sequence 1:	NP_001246912.1	Gene:	smash / 40583	FlyBaseID:	FBgn0263346	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	XP_006527864.1	Gene:	Fhl1 / 14199	MGIID:	1298387	Length:	339	Species:	Mus musculus

Alignment Length:	128	Identity:	27/128 - (21%)
Similarity:	45/128 - (35%)	Gaps:	36/128 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1447 NSSQGQEKVLSVSGKKKCSHCGDEL---------GKLCYY-----------VGCR----GAAMII 1487
            :|.....||.::|.|..|.:|.|.|         |:.|..           |.||    ..|..:
Mouse     6 HSGPSSYKVGTMSEKFDCHYCRDPLQGKKYVQKDGRHCCLKCFDKFCANTCVDCRKPISADAKEV 70

  Fly  1488 ESLLLFYHINCFKCCVC-HVQLGDGLNGTDVRV-------RNHKLHCQNCY----SSDDGIKF 1538
            .....::|.|||:|..| |....:.....|.::       |.....|:.|:    :.|..:::
Mouse    71 HYKNRYWHDNCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEY 133

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smash	NP_001246912.1	DUF4757	14..152	CDD:292571
smash	NP_001246912.1	LIM	<1494..1530	CDD:278823	10/43 (23%)
Fhl1	XP_006527864.1	LIM	<21..49	CDD:351770	6/27 (22%)
		LIM1_FHL1	56..109	CDD:188730	12/52 (23%)
		LIM2_FHL1	117..174	CDD:188808	3/17 (18%)
		LIM3_FHL1	178..230	CDD:188813
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900