DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spartin and AT3G51250

DIOPT Version :9

Sequence 1:	NP_001246910.1	Gene:	spartin / 40582	FlyBaseID:	FBgn0037265	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_190693.1	Gene:	AT3G51250 / 824288	AraportID:	AT3G51250	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	108/495 - (21%)
Similarity:	175/495 - (35%)	Gaps:	143/495 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 QSIDDSAVEATEESRAEMDTKRPPL----LAENPSTQYGIA----NASGAPKTYRELAAGLRELL 158
            |||.|:...:|....|......|.|    |..|....:|.|    :.|..|:...|:      |:
plant    21 QSIPDNPFASTNPYVASSPYLYPSLSSHNLGPNLFPDHGDASNDQSPSAPPQATEEV------LI 79

  Fly   159 AVRDAKV-LLDELFRAQVKMYRIE-ASGSVT---TISGSSTMSLVMCTVGG--KW---------K 207
            .|..|.: |:|       |.|.:| |.|..|   .|.|.:.:: |:..||.  :|         |
plant    80 RVPGAILNLID-------KSYSVELACGDFTIVRIIQGQNIVA-VLANVGNEIQWPLTKNEVAAK 136

  Fly   208 YLSGIYFIQCSMPNEGTAGIWLYPLVPSITNCYQTEYGAFIFPDMECQQPGNA----------FG 262
            .....||.....|.|...|                 .|:    |.:.:|...:          :|
plant   137 VDGSHYFFSIHPPKEKGQG-----------------SGS----DSDDEQGQKSKSKSDDEILNYG 180

  Fly   263 LMLTKEGQTSRTEDELEDLQQFFLDLL---------------EAVLAGTVVQLKSPTSQRAGLAS 312
            |.:..:||    |:.|..|.|...|..               |.||..:||...|| .:..|...
plant   181 LTIASKGQ----ENVLLVLDQVLRDYSCFTEQRMSEKAKETGEEVLGNSVVADTSP-EELKGERK 240

  Fly   313 DTVSG---------SEQVSRHIVSAADFIAS---NLVRG----AEKTGGFMLRSTPYIISKMTPA 361
            |.|.|         :..|..:..|.|..|||   .|:||    .:.|...:.:....:.::::.|
plant   241 DVVEGQCAAYWTTLAPNVEDYTHSTAKMIASGSGKLIRGILWCGDVTVERLKKGNEVMKNRLSRA 305

  Fly   362 SMDAQVPSSVQTSVEVAQKVTHAAAGM-TGWIAGKVG-----TASMAVGRYLAPHIQEQGSKLLQ 420
            ..:..|.......::..::||.....: ||.::|.|.     |.|||            .||..:
plant   306 EKEKDVSPETLRRIKRVKRVTQMTEKVATGVLSGVVKVSGFITGSMA------------NSKAGK 358

  Fly   421 KGFGYDTSEANSTMEGAMTIAAGAVEGVSTVFDGLETSAKILGSSLSENSVKIIEHKYGQQTGNL 485
            |.||        .:.|.:.:|  :::|.|.:.|.:|.:.|.:.|:.|..:.:::.|:||.:....
plant   359 KLFG--------LLPGEIVLA--SLDGFSKICDAVEVAGKNVMSTSSTVTTELVNHRYGTKAAEA 413

  Fly   486 ASGTFDTVGNVFVVS----------QNVNYITPKGIAKKM 515
            .:...|..|:.|..:          ...|.|.|..:||.:
plant   414 TNEGLDAAGHAFGTAWVAFKIRKAFNPKNVIKPSSLAKSV 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spartin	NP_001246910.1	MIT_spastin	15..97	CDD:239142
spartin	NP_001246910.1	Senescence	325..511	CDD:284359	44/208 (21%)
AT3G51250	NP_190693.1	Senescence	269..437	CDD:399715	39/189 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21068
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100