DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spartin and ERD7

DIOPT Version :9

Sequence 1:	NP_001246910.1	Gene:	spartin / 40582	FlyBaseID:	FBgn0037265	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_179374.1	Gene:	ERD7 / 816293	AraportID:	AT2G17840	Length:	452	Species:	Arabidopsis thaliana

Alignment Length:	459	Identity:	86/459 - (18%)
Similarity:	165/459 - (35%)	Gaps:	144/459 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 DTKRPPLLAENPSTQYGIANASGA-----PKTYR-ELAAGLRELLAVRDAKVLLDELFRAQVKMY 178
            :|...|:.|...:|:..|...|||     .|:|. |||.|..|::.:
plant    55 ETSSIPVSAPPAATEEVILKISGAILHLIDKSYSVELACGDLEIIRI------------------ 101

  Fly   179 RIEASGSVTTISGSSTMSLVMCTVGGKWKYLSGIYFIQCSMPNEGTAGIWLYPLVPSITNCYQTE 243
                      :.|.:.:: |:.:|..:         ||             :||... .|..:.:
plant   102 ----------VQGENVVA-VLASVSDE---------IQ-------------WPLTKD-ENSVKVD 132

  Fly   244 YGAFIFP---------DMECQQPGNA---------FGLMLTKEGQTS---RTEDELEDLQQFFLD 287
            ...:.|.         |...::.|:.         :||.:..:||..   ..|..|||...|.:.
plant   133 ESHYFFTLRPTKEISHDSSDEEDGDGGKNTNEMLNYGLTIASKGQEHLLVELEKILEDYSSFSVQ 197

  Fly   288 LL--------EAVLAGTVVQLKSP---TSQR----------------------AGLASDTV-SGS 318
            .:        |.||..||.:..||   |.:|                      :|.|:..: :||
plant   198 EVSEEAKEAGEKVLDVTVARETSPVELTGERKEIVERQCSAYWTTLAPNVEDYSGKAAKLIATGS 262

  Fly   319 EQVSRHIVSAADFIASNLVRGAEKTGGFMLRSTPYIISKMTPASMDAQVPSSVQTSVEVAQKVTH 383
            ..:.:.|:...|.....|:.|    .|||.|       :::.|..:::|.......:...:::|.
plant   263 GHLIKGILWCGDVTMDRLIWG----NGFMKR-------RLSKAEKESEVHPDTLKRIRRVKRMTK 316

  Fly   384 AAAGMTGWIAGKVGTASMAVGRYLAPHIQEQGSKLLQKGFGYDTSEANSTMEGAMTIAAGAVEGV 448
                ||..:|..:.:..:.|..:....:  ..:|:.:|.|        |.:.|.:.:|  :::|.
plant   317 ----MTESVANSILSGVLKVSGFFTSSV--ANTKVGKKFF--------SLLPGEVILA--SLDGF 365

  Fly   449 STVFDGLETSAKILGSSLSENSVKIIEHKYGQQTGNLASGTFD----TVGNVFVVSQNVNYITPK 509
            :.|.|.:|.:.:.:.|:.|..:.::::||||.:.....:...|    .:|..:|..:....|.||
plant   366 NKVCDAVEVAGRNVMSTSSTVTTELVDHKYGGKAAEATNEGLDAAGYALGTAWVAFKIRKAINPK 430

  Fly   510 GIAK 513
            .:.|
plant   431 SVLK 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spartin	NP_001246910.1	MIT_spastin	15..97	CDD:239142
spartin	NP_001246910.1	Senescence	325..511	CDD:284359	37/189 (20%)
ERD7	NP_179374.1	Senescence	258..426	CDD:399715	36/194 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21068
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100