Protein Alignment rpk and scnn1b

DIOPT Version :10

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 616
• Identity: 129/616 - (20%)
• Similarity: 204/616 - (33%)
• Gaps: 185/616 - (30%)

  Fly    35 TYHE----YCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGCSTLIQSAYTKWTETPVIVSF 95
            ||.|    :|.||:.||.:.: .:|.| ::|:.|..:         ||:.:....|....:|:::
 Frog    27 TYKELLVWFCDNTNTHGPKRI-IKEGP-KKRVMWFIL---------TLVFAGLVFWQWGVLILTY 80

  Fly    96 AEKSTPV------WNIPFPAVTVC-------SETKRVLKQKGKETTYADLYSQFSEDMRASRVFR 147
            ......|      ..:.|||||||       |..|.:||                 |:.|.....
 Frog    81 LSYGVSVSLSIGFKTMEFPAVTVCNANPYKYSRVKPLLK-----------------DLDALVATA 128

  Fly   148 PENVSALEMEEFRTLLHVCNTQIIEED------IPLIAGDDLDYFDVLQRMLPQFDRYFFYCRWL 206
            .:.:.....::..|.......|.:..|      |||:..|:.|..:.:...:  ||....|.:
 Frog   129 LDRIQFSSQDQANTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNI--FDNNAIYSK-- 189

  Fly   207 SRFGECETFFRKTLTEEGICY-----------TFNGLRATEIYRDDT---------YQYQHS--- 248
                  ...||.: :|:...|           |.|..:.  :||:.|         |..|.|
 Frog   190 ------NNSFRNS-SEDQTSYSQRYKVAMKLCTNNNTQC--VYRNFTSGIQALQEWYLLQLSSIF 245

  Fly   249 -------------------------GEPLEMENISSQHTA---------WTLETGYALDSDVETF 279
                                     |:|....|.:..:.|         |..|     ..|
 Frog   246 SNVPLADRIAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNWGQE-----GED---- 301

  Fly   280 PARVLSAGARSGIFLALQSFKQE-VDYACRGPVQGFKVGKFENVLLHAPDDVPQVSKQFVRIPMG 343
            |....:.||..|:.|.|...:.| :.|     ||.....:   ::||.....|.|....:....|
 Frog   302 PMASANPGADFGLKLVLDIEQGEYLPY-----VQTTAAAR---LILHQQRSFPFVKDLGIYAMPG 358

  Fly   344 KEVLIAVKPNMITMSSGIAEYH---------PVRRQCFLSHERSLRFFKVYTESNCQLECLANFT 399
            .|..|||..:.:....  |.|.         ||:.   |..|    |...|:..:|...|.....
 Frog   359 TETSIAVLVDQLEHME--APYSSCTVNGSDIPVQN---LYAE----FNSSYSIQSCLRSCYQEQM 414

  Fly   400 LTKCGCVKFSMPRNVDMPVCGEDK----IHCYDRAERELLVREFKRVKALNAGRENSRSVESACN 460
            :..|||..:..|.......|..||    :.||......:            |.||:..|:
 Frog   415 VQTCGCADYQYPLPNGSEYCSNDKYPDWVPCYYGLRDSV------------ADRESCISL----- 462

  Fly   461 CMPACTSLVYNTEISQANFD-------LEEMLVAEGDTEFLKEYPGSQMSRLSIYFKQSQFITSK 518
            |...|....|...||.|::.       :..:|..|.|:........:.:.||:|||::..:.:..
 Frog   463 CQQPCNDTQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRSIT 527

  Fly   519 RSELYGMTEFLANCGGIFGLFMGFSILSLVE 549
            .||...:...|:|.||.||.:||.|:|.::|
 Frog   528 ESEATNVVWLLSNLGGQFGFWMGGSVLCIIE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:459966	126/608 (21%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	129/616 (21%)