DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rpk and ppk24

DIOPT Version :9

Sequence 1:	NP_001246909.1	Gene:	rpk / 40580	FlyBaseID:	FBgn0022981	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_651860.2	Gene:	ppk24 / 43702	FlyBaseID:	FBgn0039839	Length:	595	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	131/596 - (21%)
Similarity:	214/596 - (35%)	Gaps:	163/596 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FITTYHEYCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGCSTLIQ---SAYTKWTETPVIV 93
            |.....:..:|.|.|....|.|..|..:||.|| |||.|:  ..:.||.   ..|||..|. ::.
  Fly    57 FAAALKDLLQNLSFHCYSKLVESGRRIQERFFW-FVFHIT--ALTVLIAFLWGTYTKEQEA-LVT 117

  Fly    94 SFAEKSTPVWNIPFPAVTVCSETKRVLKQ---------KGKETTYADLYSQFSEDMRASRVFRPE 149
            :......|:|.:.|||::||| ..|:.::         .||:....:. |.|.:.::|......:
  Fly   118 TMYHPMYPIWKVEFPAISVCS-LNRISQRAAWQYAHNLSGKDPKQRNA-SHFYDQLKAFMYMYYD 180

  Fly   150 NVSALEME---EFRTLLHVCNTQIIEEDIPLIAGDDLDYFDVLQRM---LPQFDRYFFYCRWLSR 208
            ....::::   .|::.|...:|          |.::| :|:...||   .|.....|..||...|
  Fly   181 PSDLMDIDNALRFQSFLDRFDT----------AKEEL-FFNTRNRMSALTPNCSDMFVSCRIAGR 234

  Fly   209 FGECETFFRKTLTEEGICYTFNGLRATEIYRDDTYQYQHSGEPLEMENISSQHTAWTLETGYALD 273
            ..:|...|..|||..|.|.|||                :.|..:...:...::
  Fly   235 LFDCMDKFETTLTSHGFCCTFN----------------YDGRYVNKRDFRQRY------------ 271

  Fly   274 SDVETFPARVLSAGARSGIFLALQSFKQEVDYACRG------PVQGFKVGKFE-------NVLLH 325
                        .|...|:.|.|::...:..|...|      |..|   |..|       |.||
  Fly   272 ------------FGPDMGLVLTLKTDPSDNFYKINGHNGYPDPFSG---GVAERVAETGFNTLL- 320

  Fly   326 APDDVPQVSKQFVRIPMGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFKVYTESNC 390
                 |..:|.|..:|..:           :||       |..|:|...:|....|.:.||.|.|
  Fly   321 -----PVRAKIFETLPEAR-----------SMS-------PSVRKCLFENEMPWIFARHYTFSKC 362

  Fly   391 QLECLANFTLTKCGCVKFSMP-RNVDMPVCGEDKIHCYDRAERELLVREFKRVKALNAGRENSRS 454
            ...|.|...::.|.||.||:| |.:|   ..|.:|:|..:....|...|||.:..:.: |||...
  Fly   363 ISACRAQSVVSLCECVPFSLPHRYID---GSEKRIYCTLQHLACLKRYEFKWLNVITS-RENVTG 423

  Fly   455 VESACN-------CMPACTSLVYNTEISQANFDLEEMLVAEGDTEFLKEYPG------------- 499
            :|....       |:.:||...|:.. ......|......:|..   :..||
  Fly   424 LEHELQDALYCPLCLASCTETRYSVR-GAMTLGLPTPSQIKGPA---RSNPGPRANNSYGPASSS 484

  Fly   500 -------------SQMSRLSIYFKQSQ---FITSKRSELYGMTEFLANCGGIFGLFMGFSILSLV 548
                         ::::.:.|||.::.   |....:|..|   |..:..|.|.|:..|||::.:.
  Fly   485 GSAKGPVHSSSAPAELAVVRIYFAETHIQYFRQIIKSAWY---ETFSTIGNICGIIAGFSLIGIC 546

  Fly   549 EMIYHFTLRLF 559
            |:::....:|:
  Fly   547 ELLFFLAKQLW 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	129/580 (22%)
ppk24	NP_651860.2	ASC	65..551	CDD:279230	129/580 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456698
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	7	6.850