Protein Alignment rpk and asic1c

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_021325802.1
• Gene: asic1c / 407670
• ZFINID: ZDB-GENE-040513-3
• Length: 562
• Species: Danio rerio
• Alignment Length: 564
• Identity: 120/564 - (21%)
• Similarity: 214/564 - (37%)
• Gaps: 137/564 - (24%)

  Fly    33 ITTYHEYCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGCSTLIQSAYT-KWTETPVIVSF- 95
            |||  .:...|.:||:::.....:...:|:|||...|:    |..|:   :| .|.....::|:
Zfish    37 ITT--AFVLRTKVHGLKHAFSPHKSKTQRLFWLLALLV----CLGLL---FTWSWNRILYLLSYP 92

  Fly    96 -AEKSTPVW--NIPFPAVTVCSETKRVLKQKGKETTYADLYSQFSED-MRASRVFRPENVSALEM 156
             ..|...||  |:.|||:|.|::.:..:....::..|   ||.:..| :..:.....::||.|:.
Zfish    93 AVTKIYMVWSNNMTFPAITFCNQNRLRVSSLTRDDLY---YSGYWMDILHLNHTLNRQSVSMLKH 154

  Fly   157 EEFR-TLLHVCNTQIIEEDIPLIAGDDLDYFDVLQRMLPQFDRYFFYCRWLSRFGECETF--FRK 218
            ...| .|||:.:.......    ....|:..:::.|:..|.......||:.   ||..|:  |..
Zfish   155 SRHRERLLHLLDFSHYSPP----PDQSLNTTEMIDRLGHQLQDMLLECRFR---GENCTYKNFTP 212

  Fly   219 TLTEEGICYTFN-GLRATEIYRDDTYQYQHSGEPLEMENISSQHTAWTLETGYALDSDVETFPAR 282
            ..|..|.||||| ||               .|.||             |.|
Zfish   213 IYTRYGKCYTFNSGL---------------DGNPL-------------LTT-------------- 235

  Fly   283 VLSAGARSGIFLALQSFKQEVDYACRGPVQG------FKVGKFENVLLHAPDDVPQVSKQFVRIP 341
             |..|..:|:.:.|..  |:.:|.   ||.|      ::.|  ..|.:|:.|:.|.:.:....:.
Zfish   236 -LKGGTGNGLEIMLDI--QQDEYL---PVWGDTDETSYEAG--IKVQIHSQDEPPFIDQLGFGVA 292

  Fly   342 MGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCV 406
            .|.:..::.:..::.       |.|.......|......:|..|:.:.|:::|...:.|..|.|
Zfish   293 PGFQTFVSCQQQLLL-------YLPPPWGDCRSAPMDSEYFSTYSITACRIDCETRYLLENCNC- 349

  Fly   407 KFSMPRNVDMP----VCGEDKI-HCYDRAERELLVREFKRVKALNAGRENSRSVESACNCMPACT 466
                 |.|.||    ||..::. .|.|.|...|:.::                 ...|.|...|.
Zfish   350 -----RMVHMPGTSTVCTPEQYKDCADPALDFLVEKD-----------------NDYCVCDTPCN 392

  Fly   467 SLVYNTEISQANFDLEEMLVAEGDTEFL-------KEYPGSQMSRLSIYFKQSQFITSKRSELYG 524
            ...|..|:|...      :.::...::|       ::|....:..|.|:|:...:...::.:.|.
Zfish   393 MTRYGKELSMVK------IPSKASAKYLAKKFNKTEQYITDNILVLDIFFEALNYEKIEQKKAYE 451

  Fly   525 MTEFLANCGGIFGLFMGFSILSLVEMIYHFTLRLFTNLKRLVKG 568
            :...|.:.||..|||:|.|:|:::|:..:    |:..||..:.|
Zfish   452 VAGLLGDIGGQMGLFIGASVLTILEIFDY----LYEVLKDKILG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	113/540 (21%)
asic1c	XP_021325802.1	ASC	34..531	CDD:322155	120/564 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26495
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.970