Protein Alignment rpk and asic4b

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_999951.1
• Gene: asic4b / 407667
• ZFINID: ZDB-GENE-040513-6
• Length: 558
• Species: Danio rerio
• Alignment Length: 586
• Identity: 122/586 - (20%)
• Similarity: 208/586 - (35%)
• Gaps: 182/586 - (31%)

  Fly    20 RRRKAGSVACEGFITTYHEYCRNTSIHGV-QYLGEQER-PFRERIFWLFVFLISIYGCSTLIQSA 82
            ||:|.|......|.:       ::|:||: :.||..|| .||:.: |....|:|: |. .|.|:.
Zfish    35 RRQKEGMADLASFAS-------SSSLHGLARALGTSERLGFRQTL-WGLALLVSL-GL-FLYQAT 89

  Fly    83 YTKWT--ETPVIVSFAEKSTPVWNIPFPAVTVCSETKRVLKQKGKETTYADLYSQFSEDMRASRV 145
            ::..|  |.|.:.:..|::..  .:.|||:|:|:    |.:.:....|.||:|
Zfish    90 WSAATYLERPHLAALREETRR--ELTFPAITLCN----VNRFRFSALTDADIY------------ 136

  Fly   146 FRPENVSALEMEEFRTLLHVCNTQIIEEDIPLIAG-----------DDLDY-----FDVLQRMLP 194
                              |:.|          :.|           .:|.|     .|:.||...
Zfish   137 ------------------HLAN----------LTGLPPKSRKGHRPSELQYPPPNMLDIFQRTGH 173

  Fly   195 QFDRYFFYCRWLSRFGECETFFRKTLTEEGICYTFNGLRATEIYRDDTYQYQHSGEPLEMENISS 259
            |.:.....|.:..:....|. |....|..|.||||||.:
Zfish   174 QLEDMLKSCNFSGQNCSSED-FSVVYTRYGKCYTFNGNK-------------------------- 211

  Fly   260 QHTAWTLETGYALDSDVETFPARVLSAGARSGIFLALQSFKQEVDYACRGPV----------QGF 314
                              |.|.||...|..:|:.:.|..  |:.:|.   |:          .|.
Zfish   212 ------------------TSPKRVRQGGTGNGLEMMLDI--QQDEYL---PIWRETNETTLEAGI 253

  Fly   315 KVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKPNMITMSSGIAEYHPVR-RQCFLSHERS 378
            :      |.:|:.::.|.:.:....:..|.:..::.:...:|       |.|.. ..|..|.|..
Zfish   254 R------VQIHSQNEPPYIHQLGFGVSPGFQTFVSCQEQRLT-------YLPQPWGNCRASSEPV 305

  Fly   379 LRFFKVYTESNCQLECLANFTLTKCGCVKFSMPRNVDMPVCGEDKIHCYDRAERELLVREFKRVK 443
            :..:..|:.|.|:|.|.:.....:|.|....||.:.|  :|...||.|.|:|...|
Zfish   306 IPGYDTYSVSACRLHCESTQVQRECNCRMVHMPGDAD--ICAPSKIKCVDKALASL--------- 359

  Fly   444 ALNAGRENSRSVESACNCMPACTSLVYNTEISQANFDLEEMLVAEGDTEFL-------KEYPGSQ 501
                    .:|...:|.|...|....|..|:|...      :.:.|...:|       :||....
Zfish   360 --------QKSTGDSCPCETPCNLTRYGKELSMVK------IPSRGSARYLSRKYQKSEEYIRDN 410

  Fly   502 MSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMIYHFTLRLFTNLKRLV 566
            ...|.|:|:...:.|.::.:.|.:...|.:.||..|||:|.|||:::|::.:........:|:|:
Zfish   411 FLILDIFFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYIYEVAKNKIKQLL 475

  Fly   567 K 567
            |
Zfish   476 K 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	114/550 (21%)
asic4b	NP_999951.1	ASC	54..497	CDD:295594	116/560 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26504
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.870