Protein Alignment rpk and Asic3

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 583
• Identity: 111/583 - (19%)
• Similarity: 186/583 - (31%)
• Gaps: 185/583 - (31%)

  Fly    20 RRRKAGSVACEGFITTYHEYCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGCSTLIQSAYT 84
            :||:|..:         ..:..:.::||:.::.........|..|....|:|:......:.....
  Rat    11 QRRQASDI---------RVFASSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVR 66

  Fly    85 KWTETPVIVSFAEKST----PVWNIPFPAVTVCSETKRVLKQKGKETTYADLYSQFSEDMRASRV 145
            .:.|      |..|:|    ....:.|||||:|:                      ...:|.||:
  Rat    67 YYGE------FHHKTTLDERESHQLTFPAVTLCN----------------------INPLRRSRL 103

  Fly   146 FRPENVSALEMEEFRTLLHVCNTQIIEEDIPLIAGDDLDYFDVLQR--------MLPQFDRYFFY 202
             .|.:            ||...|.::..|    ..:...|...|.:        ..|.||....|
  Rat   104 -TPND------------LHWAGTALLGLD----PAEHAAYLRALGQPPAPPGFMPSPTFDMAQLY 151

  Fly   203 -------------CRWLSRFGEC-ETFFRKTLTEEGICYTFNGLRATEIYRDDTYQYQHSGEPLE 253
                         ||:  |...| ...|....|..|.|||||
  Rat   152 ARAGHSLEDMLLDCRY--RGQPCGPENFTVIFTRMGQCYTFN----------------------- 191

  Fly   254 MENISSQHTAWTLETGYALDSDVETFPARVLSAGARSGIFLALQSFKQEVDYACRGPV------Q 312
                |..|.|..|.|.               ..||.:|:.:.|.  .|:.:|.   |:      .
  Rat   192 ----SGAHGAELLTTP---------------KGGAGNGLEIMLD--VQQEEYL---PIWKDMEET 232

  Fly   313 GFKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLIAVKPNMI-----------TMSSGIAEYHP 366
            .|:||  ..|.:|:.|:.|.:.:.......|.:..::.:...:           |.|....::.|
  Rat   233 PFEVG--IRVQIHSQDEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASLDPDDFDP 295

  Fly   367 VRRQCFLSHERSLRFFKVYTESNCQLECLANFTLTKCGCVKFSMPRNVDMPVCGEDKI-HCYDRA 430
            ..... |...|. |....|:...|:|.|.:.:...||||....||.|  .|||...:. .|...|
  Rat   296 EPSDP-LGSPRP-RPSPPYSLIGCRLACESRYVARKCGCRMMHMPGN--SPVCSPQQYKDCASPA 356

  Fly   431 ERELLVREFKRVKALNAGRENSRSVESACNCMPACTSLVYNTEISQANFDLEEMLVAEGDTEFL- 494
            ...:|.::                   .|.|...|.:..|..|:|...      :.:.....:|
  Rat   357 LDAMLRKD-------------------TCVCPNPCATTRYAKELSMVR------IPSRASARYLA 396

  Fly   495 ------KEYPGSQMSRLSIYFKQSQFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMI 551
                  :.|....:..|.|:|:...:...::...|.::|.|.:.||..|||:|.|:|:::|::
  Rat   397 RKYNRSESYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEIL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	108/564 (19%)
Asic3	XP_038963092.1	ASC	17..547	CDD:413546	108/577 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.820