Protein Alignment rpk and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 136/645 - (21%)
• Similarity: 212/645 - (32%)
• Gaps: 219/645 - (33%)

  Fly    35 TYHE----YCRNTSIHGVQYLGEQERPFRERIFWLFVFLISIYGC---STLIQSAYTKWTETPVI 92
            ||.|    ||.||:.||.:.: ..|.|.::.:::|...|.:...|   ...||: |..| |..|.
  Rat    21 TYKELLVWYCNNTNTHGPKRI-ICEGPKKKAMWFLLTLLFACLVCWQWGVFIQT-YLSW-EVSVS 82

  Fly    93 VSFAEKSTPVWNIPFPAVTVC-------SETKRVLKQKGKETTYADLYSQFSEDMRASRVFRPE- 149
            :|...|:     :.|||||||       |:.|.:||         |||......:  .::..|:
  Rat    83 LSMGFKT-----MNFPAVTVCNSSPFQYSKVKHLLK---------DLYKLMEAVL--DKILAPKS 131

  Fly   150 --------------NVSALEMEEFRTLLH--------------------VCNTQIIEEDIPLIAG 180
                          |.:.|.:.:.|...|                    .||.|..:..:.|.:.
  Rat   132 SHTNTTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSA 196

  Fly   181 DD--------------------LDYFDVLQRMLPQF--------DRYFFYCRWLSRFGECETFFR 217
            :.                    |...::..::|||.        ||....|    .|| .|....
  Rat   197 NGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILAC----LFG-TEPCSH 256

  Fly   218 KTLT-----EEGICYTFNGLRATEIYRDDTYQYQHSGEPLEMENISSQHTAWTLETGYALDSDVE 277
            :..|     :.|.||.||                                 |.: |..||.|
  Rat   257 RNFTPIFYPDYGNCYIFN---------------------------------WGM-TEKALPS--- 284

  Fly   278 TFPARVLSAGARSGIFLALQSFKQEVDYACRGPVQGFKVGKFENVLLHAPDDVPQVSKQFVRIPM 342
                  .:.|...|:.|.| ...|| ||.   |......|  ..::||.....|.:.::.:....
  Rat   285 ------ANPGTEFGLKLIL-DIGQE-DYV---PFLASTAG--ARLMLHEQRTYPFIREEGIYAMA 336

  Fly   343 GKEVLIAVKPNMITMSSGIAE-YHPVRRQCFLSHERSLRFFKVYTESN-------CQLECLANFT 399
            |.|..|.|   ::....|..| |.|    |.::.. .:....:|::.|       |...|..:..
  Rat   337 GTETSIGV---LLDKLQGKGEPYSP----CTMNGS-DVAIQNLYSDYNTTYSIQACLHSCFQDHM 393

  Fly   400 LTKCGCVKFSMP--------RNVDMPVCGEDKIHCYDRAERELLVREFKRVKALNAGRENSRSVE 456
            :..|.|..:..|        .|.|.|    |..:||...:..::.||
  Rat   394 IHNCSCGHYLYPLPAGEKYCNNRDFP----DWAYCYLSLQMSVVQRE------------------ 436

  Fly   457 SAC--NCMPACTSLVYNTEISQANFDLE-------EMLVAEGDTEFLKEYPGSQMSRLSIYFKQS 512
             .|  .|..:|....|...||.|::..|       .:|..|.|...........:.:|:|||::.
  Rat   437 -TCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEF 500

  Fly   513 QFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVE-------MIYHFTLRLFTNLKRL 565
            .:.|.:.|....:...|:|.||.||.:||.|:|.|:|       .|:...::|..:.|.|
  Rat   501 NYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGL 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	129/622 (21%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	136/645 (21%)
		deg-1	29..538	CDD:273309	128/613 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720