Protein Alignment rpk and Scnn1g

DIOPT Version :9

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_035456.1
• Gene: Scnn1g / 20278
• MGIID: 104695
• Length: 655
• Species: Mus musculus
• Alignment Length: 627
• Identity: 126/627 - (20%)
• Similarity: 221/627 - (35%)
• Gaps: 186/627 - (29%)

  Fly    37 HEYCRNTSIHGVQYLGEQERPFRERIFWLFVFL----ISIYGCSTLIQSAYTKWTETPVIVSFAE 97
            |.||.||:.||.:.:.......| |:.|:...|    :.|:.|:.|:.|.||  ....:.|.|.:
Mouse    30 HWYCLNTNTHGCRRIVVSRGRLR-RLLWIAFTLTAVALIIWQCALLVFSFYT--VSVSIKVHFQK 91

  Fly    98 KSTPVWNIPFPAVTVC------------------SETKRVL-------------KQKGKE----- 126
                   :.|||||:|                  ||||:.|             .:|.:|
Mouse    92 -------LDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPRKRREAGSMR 149

  Fly   127 TTYADLYSQF-----------SEDMRASRVF--RPENVSALEMEEFRTLLHVCNTQIIEEDIPLI 178
            :|:.....:|           :|..:|...|  |...:|...:.:...::||      .|...|:
Mouse   150 STWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHV------HESKKLV 208

  Fly   179 AGDDLDYFDVLQRMLPQFDRYFFYCRWLSRFGECETFFRKTLTEEGICYTF-NGLRATEIYRDDT 242
            .                    |..|.  :...:|.|            ||| :|:.|.:.:....
Mouse   209 G--------------------FQLCS--NDTSDCAT------------YTFSSGINAIQEWYKLH 239

  Fly   243 YQYQHSGEPLEMENISSQHTAWTLETGYALDS---DVETFP------------------ARVLS- 285
            |....:..||| :.|:..::|..|......|.   |...|.                  |.:||
Mouse   240 YMNIMAQVPLE-KKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILST 303

  Fly   286 --AGARSGIFLALQSFKQEVDYACRGPVQGFKVGKFENVLLHAPDDVPQVSKQFVRIPMGKEVLI 348
              .|:..|:.:.|  :..|.:|   .|......|  ..||:|..::.|.:.      .:|.|:..
Mouse   304 SMGGSEYGLQVIL--YINEDEY---NPFLVSSTG--AKVLVHQQNEYPFIE------DVGTEIET 355

  Fly   349 AVKPNM---ITMSSGIAEYHPVRRQCFLSHERS-----LRFFKVYTESNCQLECLANFTLTKCGC 405
            |:..::   :|.|..::|.:   .||  :.:.|     ..:...|:...|...|.....:.||||
Mouse   356 AMSTSIGMHLTESFKLSEPY---SQC--TEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGC 415

  Fly   406 VKFSMPRNVDMPVCGEDK----IHCYDRAERELLVREFKRVKALNAGRENSRSVESACN--CMPA 464
            .::|.|.......|...:    ::||.:. .:..|||                 |..|.  |..:
Mouse   416 AQYSQPLPPAANYCNYQQHPNWMYCYYQL-YQAFVRE-----------------ELGCQSVCKQS 462

  Fly   465 CTSLVYNTEISQANFDLE-------EMLVAEGDTEFLKEYPGSQMSRLSIYFKQSQFITSKRSEL 522
            |:...:....|.|.:..|       .:|..:...:..|:...:.:::|.|::|.....:...|..
Mouse   463 CSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPA 527

  Fly   523 YGMTEFLANCGGIFGLFMGFSILSLVEMIYHFTLRLFTNLKR 564
            ..:...|:|.||..||:|..|::.::|:|..|.:..|:.:.|
Mouse   528 NSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIAR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:279230	121/611 (20%)
Scnn1g	NP_035456.1	ENaC	24..636	CDD:273304	126/627 (20%)
		deg-1	32..557	CDD:273309	121/611 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..636

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720