Protein Alignment rpk and mec-10

DIOPT Version :10

• Sequence 1: NP_001246909.1
• Gene: rpk / 40580
• FlyBaseID: FBgn0022981
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_509438.1
• Gene: mec-10 / 181101
• WormBaseID: WBGene00003174
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 689
• Identity: 139/689 - (20%)
• Similarity: 232/689 - (33%)
• Gaps: 219/689 - (31%)

  Fly     7 ELDSSKGIDLTFRRRRKAGSVACEGFITTYH--EYCRNTSIHGVQYLGEQERPFRERIFWLFVFL 69
            |:|.::   |::|.|.:            :|  ::|..||.||:..||:..... .|..|:|:.|
 Worm    81 EIDPTR---LSYRERIR------------WHLQQFCYKTSSHGIPMLGQAPNSL-YRAAWVFLLL 129

  Fly    70 IS----IYGCSTLIQSAYTKWTE-TPVIVSFAEKSTPVWNIPFPAVTVCSET------------- 116
            |.    |.....:||. |.|..: |.:.:.|.       ..||||:|:|:..
 Worm   130 ICAIQFINQAVAVIQK-YQKMDKITDIQLKFD-------TAPFPAITLCNLNPYKDSVIRSHDSI 186

  Fly   117 -------KRVLKQKG----------KETTYADLYSQFSEDMRASR------VFRPENVSALEMEE 158
                   |.|:|:.|          :||.| |:.....:..|..|      .|.|.| ||.|.:|
 Worm   187 SKILGVFKSVMKKAGDSSSEALEEEEETEY-DMNGITIQAKRKKRGAGEKGTFEPAN-SACECDE 249

  Fly   159 FRTLLHVCNTQIIEEDIPLIAGDDLDYFDVLQRMLPQFDRY---FFYC----RWLSRFGECETFF 216
             ....:.|..:..|:.    :||:       ...:..|||.   .:.|    :|.:.  .|:
 Worm   250 -EDGSNECEERSTEKP----SGDN-------DMCICAFDRQTNDAWPCHRKEQWTNT--TCQ--- 297

  Fly   217 RKTLTEEGIC--YTFNGLRATEIYRDDTYQYQHSGEPLEMEN-----ISSQHTAWTLET----GY 270
              |..|..:|  ....|.:.:|:.:          ||...|:     |..:|.|..|..    |.
 Worm   298 --TCDEHYLCSKKAKKGTKRSELKK----------EPCICESKGLFCIKHEHAAMVLNLWEYFGD 350

  Fly   271 ALD-SDVETFPARVLSAG-----------ARSGIFLALQSFKQE-----------VDYAC----- 307
            :.| |::.|.....|..|           |:..|..|:.:..:|           :.:.|
 Worm   351 SEDFSEISTEEREALGFGNMTDEVAIVTKAKENIIFAMSALSEEQRILMSQAKHNLIHKCSFNGK 415

  Fly   308 ----------------------------------RGPVQGFKVGKFEN--------------VLL 324
                                              .||..|.:|..|.|              :.:
 Worm   416 PCDIDQDFELVADPTFGNCFVFNHDREIFKSSVRAGPQYGLRVMLFVNASDYLPTSEAVGIRLTI 480

  Fly   325 HAPDDVPQVSKQFVRIPMGKEVLIAVKPNMITMSSGIAEYHPVRRQCFLSHERSLRFFK--VYTE 387
            |..||.|.........|.|  .:.:....|..||...|.|    ..|......|...:|  .|:.
 Worm   481 HDKDDFPFPDTFGYSAPTG--YISSFGMRMKKMSRLPAPY----GDCVEDGATSNYIYKGYAYST 539

  Fly   388 SNCQLECLANFTLTKCGCVKFSMPRNVDMP-VCGEDKIHCYDRAERELLVREFKRVKALNAGREN 451
            ..|...|.....:.:|||   |.||   .| :.|......:::..||.|.:...::..::...:
 Worm   540 EGCYRTCFQELIIDRCGC---SDPR---FPSIGGVQPCQVFNKNHRECLEKHTHQIGEIHGSFK- 597

  Fly   452 SRSVESACNCMPACTSLVYNTEISQANFDLEEMLVA----EGDTEFLKEYPGSQMSRLSIYFKQS 512
                   |.|...|...:|.|..|:|.:..:.:.::    |.:.|...|......:.|.::::..
 Worm   598 -------CRCQQPCNQTIYTTSYSEAIWPSQALNISLGQCEKEAEECNEEYKENAAMLEVFYEAL 655

  Fly   513 QFITSKRSELYGMTEFLANCGGIFGLFMGFSILSLVEMI 551
            .|.....||.||:.:.:|:.||..||:.|.|:::..|.:
 Worm   656 NFEVLSESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFV 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rpk	NP_001246909.1	ASC	39..552	CDD:459966	133/655 (20%)
mec-10	NP_509438.1	deg-1	99..696	CDD:273309	133/656 (20%)